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Univariable and multivariable linear regression analysis of baseline characteristics with serum levels of circulating immune checkpoint ligands in heart failure patients.

Journal: ESC Heart Failure

Article Title: Circulating immune checkpoints predict heart failure outcomes

doi: 10.1002/ehf2.14304

Figure Lengend Snippet: Univariable and multivariable linear regression analysis of baseline characteristics with serum levels of circulating immune checkpoint ligands in heart failure patients.

Article Snippet: Circulating levels of sPD‐L1 (Abcam, ab214565), sPD‐L2 (Invitrogen, BMS2215), and galectin‐9 (R&D Systems, DGAL90) were measured according to the manufacturer's protocol in sera of stable outpatient HF patients from The Vitamin D Chronic Heart Failure (VitD‐CHF) study ( n = 101).

Techniques:

Serum levels of sPD-L1 (A) and sPD-L2 (B) in healthy controls (HC) and ovarian cancer patients (EOC). Straight line within the violin plot indicates the median. ** p < 0.01, *** p < 0.001.

Journal: Frontiers in Oncology

Article Title: Soluble Programmed Death Receptor Ligands sPD-L1 and sPD-L2 as Liquid Biopsy Markers for Prognosis and Platinum Response in Epithelial Ovarian Cancer

doi: 10.3389/fonc.2019.01015

Figure Lengend Snippet: Serum levels of sPD-L1 (A) and sPD-L2 (B) in healthy controls (HC) and ovarian cancer patients (EOC). Straight line within the violin plot indicates the median. ** p < 0.01, *** p < 0.001.

Article Snippet: Serum concentrations of sPD-L1 and sPD-L2 were measured by commercial ELISA kits (R&D Systems, GmbH, Wiesbaden-Nordenstadt, Germany) using the manufacturer's protocols with minor modifications.

Techniques:

Decreased sPD-L2 serum levels in EOC patients with platinum resistance. Straight line within the violin plot indicates the median. Platinum resistance/sensitivity was available for 68 EOC patients. ** p < 0.01.

Journal: Frontiers in Oncology

Article Title: Soluble Programmed Death Receptor Ligands sPD-L1 and sPD-L2 as Liquid Biopsy Markers for Prognosis and Platinum Response in Epithelial Ovarian Cancer

doi: 10.3389/fonc.2019.01015

Figure Lengend Snippet: Decreased sPD-L2 serum levels in EOC patients with platinum resistance. Straight line within the violin plot indicates the median. Platinum resistance/sensitivity was available for 68 EOC patients. ** p < 0.01.

Article Snippet: Serum concentrations of sPD-L1 and sPD-L2 were measured by commercial ELISA kits (R&D Systems, GmbH, Wiesbaden-Nordenstadt, Germany) using the manufacturer's protocols with minor modifications.

Techniques:

Association of decreased sPD-L2 serum levels (pg/ml) with the presence of circulating tumor cells (CTC) and the ERCC1+CTC subpopulation. Data about the presence of CTC (A) or ERCC1+CTC (B) was available for 82 and for 57 EOC patients, respectively. Straight line within the violin plot indicates the median. **** p < 0.0001.

Journal: Frontiers in Oncology

Article Title: Soluble Programmed Death Receptor Ligands sPD-L1 and sPD-L2 as Liquid Biopsy Markers for Prognosis and Platinum Response in Epithelial Ovarian Cancer

doi: 10.3389/fonc.2019.01015

Figure Lengend Snippet: Association of decreased sPD-L2 serum levels (pg/ml) with the presence of circulating tumor cells (CTC) and the ERCC1+CTC subpopulation. Data about the presence of CTC (A) or ERCC1+CTC (B) was available for 82 and for 57 EOC patients, respectively. Straight line within the violin plot indicates the median. **** p < 0.0001.

Article Snippet: Serum concentrations of sPD-L1 and sPD-L2 were measured by commercial ELISA kits (R&D Systems, GmbH, Wiesbaden-Nordenstadt, Germany) using the manufacturer's protocols with minor modifications.

Techniques: