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Summary of throughput, length, quality, and cost of current versions of genomic sequencing.

Journal: Journal of Translational Medicine

Article Title: Genomic sequencing in clinical trials

doi: 10.1186/1479-5876-9-222

Figure Lengend Snippet: Summary of throughput, length, quality, and cost of current versions of genomic sequencing.

Article Snippet: Illumina , 5,000 Mb/day , 100 nt , 10 -2 -10 -3 , ~$0.50/Mb , Complex genomes, counting (SAGE, CNV Chip, small RNA), mRNAs, structural variation, bisulfite data, indexing SNPs, etc. , Amplification, mixed clusters/neighbor interference, phasing, base labeling , Lower cost, widely adopted platform, most well-developed bioinformatics efforts , Higher base substitution error rate, shorter reads.

Techniques: Sequencing, Amplification, Labeling