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Chemical structure and discovery of simeprevir. The section marked with the green sphere represents the two points where they connect to form a ring.

Journal: Acta Pharmaceutica Sinica. B

Article Title: Unraveling the therapeutic landscape of approved non-peptide macrocycles

doi: 10.1016/j.apsb.2025.04.021

Figure Lengend Snippet: Chemical structure and discovery of simeprevir. The section marked with the green sphere represents the two points where they connect to form a ring.

Article Snippet: Simeprevir , Hepatitis C , HCV NS3/4A protease , Janssen research & development, LLC. , 2013 , FDA.

Techniques: