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miR <t>expression</t> <t>profiles</t> in patients with VT ( DPYD 85T>C) and WT colorectal cancer. A total of 43 miRs were detected in the plasma of patients with VT (n=4) and WT colorectal cancer (n=5) using miR array. (A) Heat map of differential expression of miRs in VT compared with WT colorectal cancer. Red and green show up- and downregulation, respectively. (B) Scatter plot showing miR profiles between VT and WT colorectal cancer. Each dot represents the fold-change in expression of <t>miRNA.</t> Red, green, and black dots represent up- and downregulated and unchanged miRNAs, respectively. miR, microRNA; VT, Variant; DPYD , dihydropyrimidine dehydrogenase gene; WT, Wild type; min, minimum; avg, average; max, maximum; sn, small nuclear.
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miR <t>expression</t> <t>profiles</t> in patients with VT ( DPYD 85T>C) and WT colorectal cancer. A total of 43 miRs were detected in the plasma of patients with VT (n=4) and WT colorectal cancer (n=5) using miR array. (A) Heat map of differential expression of miRs in VT compared with WT colorectal cancer. Red and green show up- and downregulation, respectively. (B) Scatter plot showing miR profiles between VT and WT colorectal cancer. Each dot represents the fold-change in expression of <t>miRNA.</t> Red, green, and black dots represent up- and downregulated and unchanged miRNAs, respectively. miR, microRNA; VT, Variant; DPYD , dihydropyrimidine dehydrogenase gene; WT, Wild type; min, minimum; avg, average; max, maximum; sn, small nuclear.
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Image Search Results


miR expression profiles in patients with VT ( DPYD 85T>C) and WT colorectal cancer. A total of 43 miRs were detected in the plasma of patients with VT (n=4) and WT colorectal cancer (n=5) using miR array. (A) Heat map of differential expression of miRs in VT compared with WT colorectal cancer. Red and green show up- and downregulation, respectively. (B) Scatter plot showing miR profiles between VT and WT colorectal cancer. Each dot represents the fold-change in expression of miRNA. Red, green, and black dots represent up- and downregulated and unchanged miRNAs, respectively. miR, microRNA; VT, Variant; DPYD , dihydropyrimidine dehydrogenase gene; WT, Wild type; min, minimum; avg, average; max, maximum; sn, small nuclear.

Journal: Biomedical Reports

Article Title: Association between miRNA expression profiles and polymorphisms of dihydropyrimidine dehydrogenase drug-metabolizing gene in patients with colorectal cancer receiving 5-fluorouracil

doi: 10.3892/br.2025.2053

Figure Lengend Snippet: miR expression profiles in patients with VT ( DPYD 85T>C) and WT colorectal cancer. A total of 43 miRs were detected in the plasma of patients with VT (n=4) and WT colorectal cancer (n=5) using miR array. (A) Heat map of differential expression of miRs in VT compared with WT colorectal cancer. Red and green show up- and downregulation, respectively. (B) Scatter plot showing miR profiles between VT and WT colorectal cancer. Each dot represents the fold-change in expression of miRNA. Red, green, and black dots represent up- and downregulated and unchanged miRNAs, respectively. miR, microRNA; VT, Variant; DPYD , dihydropyrimidine dehydrogenase gene; WT, Wild type; min, minimum; avg, average; max, maximum; sn, small nuclear.

Article Snippet: The miRNA expression profiles were analyzed using RT-PCR with a customized miRNA array panel (cat. no. 217184; Qiagen GmbH) coated with specific primers for 43 miRNAs (sequences not provided) involved in the 5-FU metabolic pathway. miR target sequences are listed in .

Techniques: Expressing, Clinical Proteomics, Quantitative Proteomics, Variant Assay

miRNA expression profiles in patients with VT ( DPYD 1896T>C) and WT colorectal cancer. A total of 43 miRs were detected in the plasma of patients with (n=3) and WT colorectal cancer (n=3). (A) Heat map of differential expression of miRs in VT compared with WT colorectal cancer. Red and green show up- and downregulation, respectively. (B) Scatter plot showing miR profiles between VT and WT colorectal cancer. Each dot represents the fold-change in expression of miRNA. Red, green, and black dots represent up- and downregulated and unchanged miRNAs, respectively. miR, microRNA; VT, Variant; DPYD , dihydropyrimidine dehydrogenase gene; WT, Wild type; min, minimum; avg, average; max, maximum; snRNA, small nuclear RNA.

Journal: Biomedical Reports

Article Title: Association between miRNA expression profiles and polymorphisms of dihydropyrimidine dehydrogenase drug-metabolizing gene in patients with colorectal cancer receiving 5-fluorouracil

doi: 10.3892/br.2025.2053

Figure Lengend Snippet: miRNA expression profiles in patients with VT ( DPYD 1896T>C) and WT colorectal cancer. A total of 43 miRs were detected in the plasma of patients with (n=3) and WT colorectal cancer (n=3). (A) Heat map of differential expression of miRs in VT compared with WT colorectal cancer. Red and green show up- and downregulation, respectively. (B) Scatter plot showing miR profiles between VT and WT colorectal cancer. Each dot represents the fold-change in expression of miRNA. Red, green, and black dots represent up- and downregulated and unchanged miRNAs, respectively. miR, microRNA; VT, Variant; DPYD , dihydropyrimidine dehydrogenase gene; WT, Wild type; min, minimum; avg, average; max, maximum; snRNA, small nuclear RNA.

Article Snippet: The miRNA expression profiles were analyzed using RT-PCR with a customized miRNA array panel (cat. no. 217184; Qiagen GmbH) coated with specific primers for 43 miRNAs (sequences not provided) involved in the 5-FU metabolic pathway. miR target sequences are listed in .

Techniques: Expressing, Clinical Proteomics, Quantitative Proteomics, Variant Assay