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Mapping of the search strategy, methodology, and results. To assess the role of the CVM in HPV‐associated cervical carcinogenesis, 2223 records were identified in Embase, Medline and Web of Science, of which 951 duplicates were excluded. 1272 articles were screened by title and abstract for relevance and the full texts of 276 articles were assessed for eligibility. Two additional articles were identified in PubMed following the systematic search. A total of 21 observational studies, 4 systematic reviews, and 3 meta‐analyses were included. To assess the diagnostic performance of the CVM in HPV‐associated cervical carcinogenesis, 7 relevant articles were identified in PubMed, of which 3 were excluded. Of the 4 full texts assessed for eligibility, one was excluded as it only assessed the diagnostic performance of bacterial genes (not taxa). The corresponding search strategies for the aforementioned searches are detailed in Table . To identify common metagenomic techniques in microbial research, 11 resources were identified through a focused search of Google and Google Scholar to identify webpages and scholarly articles, respectively. Abbreviations: CVM, cervicovaginal microbiome; HPV, human papillomavirus; ROC, receiver operating characteristic; WMS, whole metagenome <t>sequencing;</t> 16S rRNA, 16S ribosomal RNA.
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Image Search Results


Mapping of the search strategy, methodology, and results. To assess the role of the CVM in HPV‐associated cervical carcinogenesis, 2223 records were identified in Embase, Medline and Web of Science, of which 951 duplicates were excluded. 1272 articles were screened by title and abstract for relevance and the full texts of 276 articles were assessed for eligibility. Two additional articles were identified in PubMed following the systematic search. A total of 21 observational studies, 4 systematic reviews, and 3 meta‐analyses were included. To assess the diagnostic performance of the CVM in HPV‐associated cervical carcinogenesis, 7 relevant articles were identified in PubMed, of which 3 were excluded. Of the 4 full texts assessed for eligibility, one was excluded as it only assessed the diagnostic performance of bacterial genes (not taxa). The corresponding search strategies for the aforementioned searches are detailed in Table . To identify common metagenomic techniques in microbial research, 11 resources were identified through a focused search of Google and Google Scholar to identify webpages and scholarly articles, respectively. Abbreviations: CVM, cervicovaginal microbiome; HPV, human papillomavirus; ROC, receiver operating characteristic; WMS, whole metagenome sequencing; 16S rRNA, 16S ribosomal RNA.

Journal: Journal of Medical Virology

Article Title: A Narrative Review of the Putative Etiologic Role and Diagnostic Utility of the Cervicovaginal Microbiome in Human Papillomavirus‐Associated Cervical Carcinogenesis

doi: 10.1002/jmv.70027

Figure Lengend Snippet: Mapping of the search strategy, methodology, and results. To assess the role of the CVM in HPV‐associated cervical carcinogenesis, 2223 records were identified in Embase, Medline and Web of Science, of which 951 duplicates were excluded. 1272 articles were screened by title and abstract for relevance and the full texts of 276 articles were assessed for eligibility. Two additional articles were identified in PubMed following the systematic search. A total of 21 observational studies, 4 systematic reviews, and 3 meta‐analyses were included. To assess the diagnostic performance of the CVM in HPV‐associated cervical carcinogenesis, 7 relevant articles were identified in PubMed, of which 3 were excluded. Of the 4 full texts assessed for eligibility, one was excluded as it only assessed the diagnostic performance of bacterial genes (not taxa). The corresponding search strategies for the aforementioned searches are detailed in Table . To identify common metagenomic techniques in microbial research, 11 resources were identified through a focused search of Google and Google Scholar to identify webpages and scholarly articles, respectively. Abbreviations: CVM, cervicovaginal microbiome; HPV, human papillomavirus; ROC, receiver operating characteristic; WMS, whole metagenome sequencing; 16S rRNA, 16S ribosomal RNA.

Article Snippet: , Amplicon sequencing using a sequencing platform (i.e., Pyrosequencing, Illumina MiSeq, Illumina nextSeq, PacBlo Seqel II/IIe, Nanopore) , Sequencing all genomic DNA using a sequencing platform (i.e., Illumina novaSeq, HiSeq ).

Techniques: Diagnostic Assay, Sequencing

16S rRNA gene sequencing and WMS for CVM characterization.

Journal: Journal of Medical Virology

Article Title: A Narrative Review of the Putative Etiologic Role and Diagnostic Utility of the Cervicovaginal Microbiome in Human Papillomavirus‐Associated Cervical Carcinogenesis

doi: 10.1002/jmv.70027

Figure Lengend Snippet: 16S rRNA gene sequencing and WMS for CVM characterization.

Article Snippet: , Amplicon sequencing using a sequencing platform (i.e., Pyrosequencing, Illumina MiSeq, Illumina nextSeq, PacBlo Seqel II/IIe, Nanopore) , Sequencing all genomic DNA using a sequencing platform (i.e., Illumina novaSeq, HiSeq ).

Techniques: Sequencing, Extraction, Amplification, Nanopore Sequencing, Marker, Bacteria