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BioSolveIT GmbH docking software seesar
Docking Software Seesar, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/seesar+software/seesar+software/pmc12260087-71-24-29
Average 90 stars, based on 1 article reviews
docking software seesar - by Bioz Stars, 2026-11
90/100 stars

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Related Articles

Software:

Article Title: In silico screening of selective ATP mimicking inhibitors targeting the Plasmodium falciparum Grp94.
Article Snippet: Plasmodium falciparum parasites export more than 400 proteins to remodel the host cell environment and increase its chances of surviving and reproducing.. The endoplasmic reticulum (ER) plays a central role in protein export by facilitating protein sorting and folding.. The ER resident member of the Hsp90 family, glucose-regulated protein 94 (Grp94), is a molecular chaperone that facilitates the proper folding of client proteins in the ER lumen.

Article Title: Mapping protein-metabolite interactions in E . coli by integrating chromatographic techniques and co-fractionation mass spectrometry
Article Snippet: .. The chosen binding sites were then used to perform molecular docking with the SeeSAR software v13.0.1 (BioSolveIT GmbH). ..

Article Title: Computational Exploration of Fluorocyclopentenyl-purines and-pyrimidines Derivatives as Potential Inhibitors of Epidermal Growth Factor Receptor (EGFR) for the Treatment of Breast Cancer.
Article Snippet: .. SeeSAR analysis was performed with the best derivatives using its docked complex form autodock vina to predict the virtual displays of binding interactions using analyser mode of SeeSAR software by BiosolveIT. ..

Article Title: Design, Synthesis, and Biological Evaluations of a Novel Resveratrol-Type Analogue Against VEGF
Article Snippet: .. Virtual screening was performed using SEESAR software (Version 13.0; https://www.biosolveit.de/ , accessed on 11 April 2024). .. The sample was collected and read under a microplate reader (Thermo Fisher Scientific) at a wavelength of 570 nm.

Article Title: Drug Screening of Flavonoids as Potential VEGF Inhibitors Through Computational Docking and Cell Models.
Article Snippet: .. Virtual screening was performed using SEESAR software (Version 13.0; https://www.biosolveit.de/, accessed on 11 April 2024), and the prediction of ADMET properties, including values of TPSA, Log p, HIA and so on, was performed in Optibrium mode. .. The stability test was validated by determining the intra-day and inter-day variability through HPLC analysis, which was performed on an Agilent 1200 Liquid Chromatography (Santa Clara, CA, USA) equipped with an ODS C18 column (4.6 mm × 250 mm).

Article Title: Drug Screening of Flavonoids as Potential VEGF Inhibitors Through Computational Docking and Cell Models
Article Snippet: .. Virtual screening was performed using SEESAR software (Version 13.0; https://www.biosolveit.de/ , accessed on 11 April 2024), and the prediction of ADMET properties, including values of TPSA, Log p , HIA and so on, was performed in Optibrium mode. .. The stability test was validated by determining the intra-day and inter-day variability through HPLC analysis, which was performed on an Agilent 1200 Liquid Chromatography (Santa Clara, CA, USA) equipped with an ODS C18 column (4.6 mm × 250 mm).

Binding Assay:

Article Title: Mapping protein-metabolite interactions in E . coli by integrating chromatographic techniques and co-fractionation mass spectrometry
Article Snippet: .. The chosen binding sites were then used to perform molecular docking with the SeeSAR software v13.0.1 (BioSolveIT GmbH). ..

Article Title: Computational Exploration of Fluorocyclopentenyl-purines and-pyrimidines Derivatives as Potential Inhibitors of Epidermal Growth Factor Receptor (EGFR) for the Treatment of Breast Cancer.
Article Snippet: .. SeeSAR analysis was performed with the best derivatives using its docked complex form autodock vina to predict the virtual displays of binding interactions using analyser mode of SeeSAR software by BiosolveIT. ..

other:

Article Title: In silico exploration and in vitro validation of the filarial thioredoxin reductase inhibitory activity of Scytonemin and its derivatives.
Article Snippet: Lymphatic filariasis (LF) caused by the vector borne parasitic nematode Wuchereria bancrofti is of major concern of the World Health Organization (WHO).. Lack of potential drug candidates worsens the situation.. Presently available drugs are promising in killing the microfilaria (mf) but are not effective as adulticidal therapeutics.



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( A ) Design of resveratrol-type derivatives. ( B ) Synthetic route towards RE-1. (I) 1,3-dichloropropane, NaH, THF, 0 °C-rt, 8 h; (II) pterostilbene, NaH, THF, rt, 16 h, 26%. Docking studies of RES ( C ) and RE-1 ( D ) against VEGF protein. VEGF 1–165 (PDB code: 1FLT) domain was selected as a binding site and docking studies were performed using <t>SEESAR</t> <t>software</t> (13.0 version). RES: resveratrol.
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( A ) Design of resveratrol-type derivatives. ( B ) Synthetic route towards RE-1. (I) 1,3-dichloropropane, NaH, THF, 0 °C-rt, 8 h; (II) pterostilbene, NaH, THF, rt, 16 h, 26%. Docking studies of RES ( C ) and RE-1 ( D ) against VEGF protein. VEGF 1–165 (PDB code: 1FLT) domain was selected as a binding site and docking studies were performed using <t>SEESAR</t> <t>software</t> (13.0 version). RES: resveratrol.
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( A ) Design of resveratrol-type derivatives. ( B ) Synthetic route towards RE-1. (I) 1,3-dichloropropane, NaH, THF, 0 °C-rt, 8 h; (II) pterostilbene, NaH, THF, rt, 16 h, 26%. Docking studies of RES ( C ) and RE-1 ( D ) against VEGF protein. VEGF 1–165 (PDB code: 1FLT) domain was selected as a binding site and docking studies were performed using SEESAR software (13.0 version). RES: resveratrol.

Journal: Molecules

Article Title: Design, Synthesis, and Biological Evaluations of a Novel Resveratrol-Type Analogue Against VEGF

doi: 10.3390/molecules30112345

Figure Lengend Snippet: ( A ) Design of resveratrol-type derivatives. ( B ) Synthetic route towards RE-1. (I) 1,3-dichloropropane, NaH, THF, 0 °C-rt, 8 h; (II) pterostilbene, NaH, THF, rt, 16 h, 26%. Docking studies of RES ( C ) and RE-1 ( D ) against VEGF protein. VEGF 1–165 (PDB code: 1FLT) domain was selected as a binding site and docking studies were performed using SEESAR software (13.0 version). RES: resveratrol.

Article Snippet: Furthermore, we employed SEESAR Optibrium software (version 14.0) to generate a group of predictive ADMET statistics of RE-1 and resveratrol.

Techniques: Binding Assay, Software

( A ) Design of resveratrol-type derivatives. ( B ) Synthetic route towards RE-1. (I) 1,3-dichloropropane, NaH, THF, 0 °C-rt, 8 h; (II) pterostilbene, NaH, THF, rt, 16 h, 26%. Docking studies of RES ( C ) and RE-1 ( D ) against VEGF protein. VEGF 1–165 (PDB code: 1FLT) domain was selected as a binding site and docking studies were performed using SEESAR software (13.0 version). RES: resveratrol.

Journal: Molecules

Article Title: Design, Synthesis, and Biological Evaluations of a Novel Resveratrol-Type Analogue Against VEGF

doi: 10.3390/molecules30112345

Figure Lengend Snippet: ( A ) Design of resveratrol-type derivatives. ( B ) Synthetic route towards RE-1. (I) 1,3-dichloropropane, NaH, THF, 0 °C-rt, 8 h; (II) pterostilbene, NaH, THF, rt, 16 h, 26%. Docking studies of RES ( C ) and RE-1 ( D ) against VEGF protein. VEGF 1–165 (PDB code: 1FLT) domain was selected as a binding site and docking studies were performed using SEESAR software (13.0 version). RES: resveratrol.

Article Snippet: Prediction of ADMET properties, including TPSA, Log P , intestinal absorption and so on, was conducted under Optibrium mode of SEESAR software (Version 13.0; https://www.biosolveit.de/ , accessed on 11 April 2024). a,b following Lipinski’s Rule of Five.

Techniques: Binding Assay, Software