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Optical detection of binding interactions between ACE2 and other proteins. (a) Measured light intensities over time for individual assessment of ACE2, S1X, S1Y, and BSA. (b) The measured mixed light intensities versus time for ACE2 mixed with either S1X, or S1Y, or BSA. (c) The measured ACE2-S1X interaction profile for an extended time period.

Journal: medRxiv

Article Title: Development of an Optical Assay to Detect SARS-CoV-2 Spike Protein Binding Interactions with ACE2 and Disruption of these Interactions Using Electric Current

doi: 10.1101/2020.11.24.20237628

Figure Lengend Snippet: Optical detection of binding interactions between ACE2 and other proteins. (a) Measured light intensities over time for individual assessment of ACE2, S1X, S1Y, and BSA. (b) The measured mixed light intensities versus time for ACE2 mixed with either S1X, or S1Y, or BSA. (c) The measured ACE2-S1X interaction profile for an extended time period.

Article Snippet: Two different spike S1 recombinant proteins (S1X (ProSci Cat no. 10-109) and S1Y (ProSci Cat no. 10-111)) were also purchased in the lyophilized form.

Techniques: Binding Assay