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Hippocampal volume. (A) Hippocampal ROI acquisition via sMRI technology; (B) Bilateral hippocampal (HP) volume comparison. L = left; R = right. Data are expressed as mean ± SD. * P < 0.05 vs. Normal; # P < 0.05 vs. SCH. (n = 3 in Normal group, n = 3 in SCH group, n = 3 in Treated group. Treated denotes the <t>risperidone</t> treatment group; SCH denotes the schizophrenia rat model group).
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risperidone  (Qilu Pharmaceutical)
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Hippocampal volume. (A) Hippocampal ROI acquisition via sMRI technology; (B) Bilateral hippocampal (HP) volume comparison. L = left; R = right. Data are expressed as mean ± SD. * P < 0.05 vs. Normal; # P < 0.05 vs. SCH. (n = 3 in Normal group, n = 3 in SCH group, n = 3 in Treated group. Treated denotes the <t>risperidone</t> treatment group; SCH denotes the schizophrenia rat model group).
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Hippocampal volume. (A) Hippocampal ROI acquisition via sMRI technology; (B) Bilateral hippocampal (HP) volume comparison. L = left; R = right. Data are expressed as mean ± SD. * P < 0.05 vs. Normal; # P < 0.05 vs. SCH. (n = 3 in Normal group, n = 3 in SCH group, n = 3 in Treated group. Treated denotes the <t>risperidone</t> treatment group; SCH denotes the schizophrenia rat model group).
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Hippocampal volume. (A) Hippocampal ROI acquisition via sMRI technology; (B) Bilateral hippocampal (HP) volume comparison. L = left; R = right. Data are expressed as mean ± SD. * P < 0.05 vs. Normal; # P < 0.05 vs. SCH. (n = 3 in Normal group, n = 3 in SCH group, n = 3 in Treated group. Treated denotes the risperidone treatment group; SCH denotes the schizophrenia rat model group).

Journal: Frontiers in Psychiatry

Article Title: Multimodal neuroimaging alterations in schizophrenia model rats and the modulatory effects of risperidone: a pilot study

doi: 10.3389/fpsyt.2026.1757297

Figure Lengend Snippet: Hippocampal volume. (A) Hippocampal ROI acquisition via sMRI technology; (B) Bilateral hippocampal (HP) volume comparison. L = left; R = right. Data are expressed as mean ± SD. * P < 0.05 vs. Normal; # P < 0.05 vs. SCH. (n = 3 in Normal group, n = 3 in SCH group, n = 3 in Treated group. Treated denotes the risperidone treatment group; SCH denotes the schizophrenia rat model group).

Article Snippet: Risperidone oral solution (30 mL: 30 mg; National Drug Approval Number: J20180022) was obtained from Xi’an Janssen Pharmaceutical Ltd. For administration, the solution was diluted in distilled water to create a risperidone mixture.

Techniques: Comparison