Journal: Frontiers in Pharmacology
Article Title: Bridging the gap in AMR research: validation of a standardized Galleria mellonella model to evaluate Clostridioides difficile pathogenesis and treatment efficacy
doi: 10.3389/fphar.2026.1792859
Figure Lengend Snippet: (A) Comparison of Galleria mellonella survival between toxigenic (MT-5369/RT 014/020) and non-toxigenic (ATCC 700057/RT 038) strains. (B) Comparison of Galleria mellonella survival between the reference strain R20291 /RT 027 and other strains/RTs. (C) Comparison of Galleria mellonella survival between the reference strain CD630/RT 012 and other strains/RTs.
Article Snippet: To determine the specific impact of toxin production on larval survival, the non-toxigenic reference strain (ATCC 700057/RT 038) was compared against the toxigenic strain MT-5369 (RT 014/020), which served as the primary test strain during the model optimization phase.
Techniques: Comparison