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gene exp plin1 hs00160173 m1  (Thermo Fisher)
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Differential expression analysis and identification of hub genes in breast cancer. A Volcano plots showing significantly upregulated (red) and downregulated (blue) genes in three GEO datasets ( GSE42568 , GSE29431 , GSE21422 ). B Venn diagram showing 231 overlapping differentially expressed genes (DEGs) across the three datasets. C Protein–protein interaction (PPI) network of overlapping DEGs constructed using STRING and visualized in Cytoscape. D RT-qPCR analysis of PPARG, LEP, CD36, and <t>PLIN1</t> expression in six breast cancer and five normal breast epithelial cell lines. E ROC curve analysis of hub genes showing their discriminatory power (AUC) between breast cancer and normal samples. F ELISA-based quantification of PPARG, LEP, CD36, and PLIN1 protein levels in the same cell lines, confirming reduced protein expression in cancer cells. P -value < 0.05
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gene exp plin1 rn00558672 m1  (Thermo Fisher)
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Thermo Fisher gene exp plin1 rn00558672 m1
Differential expression analysis and identification of hub genes in breast cancer. A Volcano plots showing significantly upregulated (red) and downregulated (blue) genes in three GEO datasets ( GSE42568 , GSE29431 , GSE21422 ). B Venn diagram showing 231 overlapping differentially expressed genes (DEGs) across the three datasets. C Protein–protein interaction (PPI) network of overlapping DEGs constructed using STRING and visualized in Cytoscape. D RT-qPCR analysis of PPARG, LEP, CD36, and <t>PLIN1</t> expression in six breast cancer and five normal breast epithelial cell lines. E ROC curve analysis of hub genes showing their discriminatory power (AUC) between breast cancer and normal samples. F ELISA-based quantification of PPARG, LEP, CD36, and PLIN1 protein levels in the same cell lines, confirming reduced protein expression in cancer cells. P -value < 0.05
Gene Exp Plin1 Rn00558672 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 87/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gene exp plin1 rn00558672 m1/product/Thermo Fisher
Average 87 stars, based on 1 article reviews
gene exp plin1 rn00558672 m1 - by Bioz Stars, 2026-03
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Differential expression analysis and identification of hub genes in breast cancer. A Volcano plots showing significantly upregulated (red) and downregulated (blue) genes in three GEO datasets ( GSE42568 , GSE29431 , GSE21422 ). B Venn diagram showing 231 overlapping differentially expressed genes (DEGs) across the three datasets. C Protein–protein interaction (PPI) network of overlapping DEGs constructed using STRING and visualized in Cytoscape. D RT-qPCR analysis of PPARG, LEP, CD36, and <t>PLIN1</t> expression in six breast cancer and five normal breast epithelial cell lines. E ROC curve analysis of hub genes showing their discriminatory power (AUC) between breast cancer and normal samples. F ELISA-based quantification of PPARG, LEP, CD36, and PLIN1 protein levels in the same cell lines, confirming reduced protein expression in cancer cells. P -value < 0.05
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gene exp plin1 hs01106922 m1 - by Bioz Stars, 2026-03
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Differential expression analysis and identification of hub genes in breast cancer. A Volcano plots showing significantly upregulated (red) and downregulated (blue) genes in three GEO datasets ( GSE42568 , GSE29431 , GSE21422 ). B Venn diagram showing 231 overlapping differentially expressed genes (DEGs) across the three datasets. C Protein–protein interaction (PPI) network of overlapping DEGs constructed using STRING and visualized in Cytoscape. D RT-qPCR analysis of PPARG, LEP, CD36, and PLIN1 expression in six breast cancer and five normal breast epithelial cell lines. E ROC curve analysis of hub genes showing their discriminatory power (AUC) between breast cancer and normal samples. F ELISA-based quantification of PPARG, LEP, CD36, and PLIN1 protein levels in the same cell lines, confirming reduced protein expression in cancer cells. P -value < 0.05

Journal: Hereditas

Article Title: A combined transcriptomic, epigenetic, and functional analysis identifies novel biomarkers in breast cancer

doi: 10.1186/s41065-025-00630-1

Figure Lengend Snippet: Differential expression analysis and identification of hub genes in breast cancer. A Volcano plots showing significantly upregulated (red) and downregulated (blue) genes in three GEO datasets ( GSE42568 , GSE29431 , GSE21422 ). B Venn diagram showing 231 overlapping differentially expressed genes (DEGs) across the three datasets. C Protein–protein interaction (PPI) network of overlapping DEGs constructed using STRING and visualized in Cytoscape. D RT-qPCR analysis of PPARG, LEP, CD36, and PLIN1 expression in six breast cancer and five normal breast epithelial cell lines. E ROC curve analysis of hub genes showing their discriminatory power (AUC) between breast cancer and normal samples. F ELISA-based quantification of PPARG, LEP, CD36, and PLIN1 protein levels in the same cell lines, confirming reduced protein expression in cancer cells. P -value < 0.05

Article Snippet: The following TaqMan Assay IDs were used: PPARG (Hs01115513_m1), LEP (Hs00174877_m1), CD36 (Hs00354519_m1), PLIN1 (Hs00160173_m1), and GAPDH (Hs02758991_g1).

Techniques: Quantitative Proteomics, Construct, Quantitative RT-PCR, Expressing, Enzyme-linked Immunosorbent Assay

Genomic alteration profiles of hub genes in breast cancer. A Oncoprint showing mutation frequency and types of hub genes in breast cancer samples (cBioPortal). B Heatmap of single nucleotide variant (SNV) percentages across hub genes. C Classification of mutation types, SNV classes, and mutation frequencies in hub genes. D Lollipop plots showing mutation positions across protein domains of PPARG, CD36, and PLIN1. E Pie charts illustrating copy number alterations (CNA) including amplifications and deletions for each hub gene. P -value < 0.05

Journal: Hereditas

Article Title: A combined transcriptomic, epigenetic, and functional analysis identifies novel biomarkers in breast cancer

doi: 10.1186/s41065-025-00630-1

Figure Lengend Snippet: Genomic alteration profiles of hub genes in breast cancer. A Oncoprint showing mutation frequency and types of hub genes in breast cancer samples (cBioPortal). B Heatmap of single nucleotide variant (SNV) percentages across hub genes. C Classification of mutation types, SNV classes, and mutation frequencies in hub genes. D Lollipop plots showing mutation positions across protein domains of PPARG, CD36, and PLIN1. E Pie charts illustrating copy number alterations (CNA) including amplifications and deletions for each hub gene. P -value < 0.05

Article Snippet: The following TaqMan Assay IDs were used: PPARG (Hs01115513_m1), LEP (Hs00174877_m1), CD36 (Hs00354519_m1), PLIN1 (Hs00160173_m1), and GAPDH (Hs02758991_g1).

Techniques: Mutagenesis, Variant Assay

Overexpression of CD36 and PLIN1 inhibits oncogenic behavior in MCF-7 cells. A , B mRNA and protein levels of CD36 and PLIN1 are significantly increased in MCF-7 cells transfected with expression vectors. C Overexpression significantly reduces proliferation ( p < 0.001). D , E Colony formation is markedly suppressed. F , G Wound closure is reduced, indicating decreased cell motility. P ***-value < 0.001

Journal: Hereditas

Article Title: A combined transcriptomic, epigenetic, and functional analysis identifies novel biomarkers in breast cancer

doi: 10.1186/s41065-025-00630-1

Figure Lengend Snippet: Overexpression of CD36 and PLIN1 inhibits oncogenic behavior in MCF-7 cells. A , B mRNA and protein levels of CD36 and PLIN1 are significantly increased in MCF-7 cells transfected with expression vectors. C Overexpression significantly reduces proliferation ( p < 0.001). D , E Colony formation is markedly suppressed. F , G Wound closure is reduced, indicating decreased cell motility. P ***-value < 0.001

Article Snippet: The following TaqMan Assay IDs were used: PPARG (Hs01115513_m1), LEP (Hs00174877_m1), CD36 (Hs00354519_m1), PLIN1 (Hs00160173_m1), and GAPDH (Hs02758991_g1).

Techniques: Over Expression, Transfection, Expressing

CD36 and PLIN1 overexpression reduces proliferation and migration in T47D cells. A , B Confirmation of CD36 and PLIN1 overexpression at transcript and protein levels. C Cell proliferation is significantly inhibited in both overexpression groups. D , E Fewer colonies are formed, indicating reduced clonogenic capacity. F , G Migration is impaired in wound healing assays at 24 h. P ***-value < 0.001

Journal: Hereditas

Article Title: A combined transcriptomic, epigenetic, and functional analysis identifies novel biomarkers in breast cancer

doi: 10.1186/s41065-025-00630-1

Figure Lengend Snippet: CD36 and PLIN1 overexpression reduces proliferation and migration in T47D cells. A , B Confirmation of CD36 and PLIN1 overexpression at transcript and protein levels. C Cell proliferation is significantly inhibited in both overexpression groups. D , E Fewer colonies are formed, indicating reduced clonogenic capacity. F , G Migration is impaired in wound healing assays at 24 h. P ***-value < 0.001

Article Snippet: The following TaqMan Assay IDs were used: PPARG (Hs01115513_m1), LEP (Hs00174877_m1), CD36 (Hs00354519_m1), PLIN1 (Hs00160173_m1), and GAPDH (Hs02758991_g1).

Techniques: Over Expression, Migration