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LMS percentiles for urinary MCP-1 (boys, a; girls, b) and (c) PIIINP to creatinine ratios in the HARP cohort. The 5th, 10th, 25th (dashed line), 50th (bold line), 75th (dashed line), 90th, and 95th percentiles are given. Data on boys and girls is given as blue triangles and orange dots, respectively. crea, creatinine; HARP, Hannover reference values for pediatrics; LMS, lambda-mu-sigma; MCP-1, monocyte chemoattractant protein-1; PIIINP, procollagen type III amino-terminal propeptide.

Journal: Kidney International Reports

Article Title: Kidney Injury Urine Biomarker Normal Ranges in Children

doi: 10.1016/j.ekir.2026.106348

Figure Lengend Snippet: LMS percentiles for urinary MCP-1 (boys, a; girls, b) and (c) PIIINP to creatinine ratios in the HARP cohort. The 5th, 10th, 25th (dashed line), 50th (bold line), 75th (dashed line), 90th, and 95th percentiles are given. Data on boys and girls is given as blue triangles and orange dots, respectively. crea, creatinine; HARP, Hannover reference values for pediatrics; LMS, lambda-mu-sigma; MCP-1, monocyte chemoattractant protein-1; PIIINP, procollagen type III amino-terminal propeptide.

Article Snippet: Urinary concentrations of KIM-1 (Quantikine ELISA, R&D system; MN Catalog No. DKM100; sensitivity 0.046 ng/ml), NGAL (Quantikine ELISA, R&D system; MN, Catalog No. DLCN20; sensitivity 0.04 ng/ml), DKK3 (Duo Set ELISA, R&D system; MN, Catalog No. DY1118, sensitivity 31.2 pg/ml), CHI3L1 (Quantikine ELISA, R&D system; MN, Catalog No. DC3L10; sensitivity 8.15 pg/ml), MCP-1 (Quantikine ELISA, R&D system;MN, Catalog No. DCP00; sensitivity 10 pg/ml), PIIINP (Novus Biologicals, Wiesbaden Nordenstadt, Germany, Catalog No. NBP2-76434; sensitivity 14.06 pg/ml), and EGF (Quantikine ELISA, R&D system; MN, Catalog No. DEG00; sensitivity 0.7 pg/ml) were measured using ELISA, according to the manufacturer’s protocols.

Techniques:

( A ) Scatter plots of PINP and PIIINP plasma values in controls and patients; ( B ) box plot of the PINP/PIIINP ratio in controls and patients.

Journal: International Journal of Molecular Sciences

Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

doi: 10.3390/ijms26157032

Figure Lengend Snippet: ( A ) Scatter plots of PINP and PIIINP plasma values in controls and patients; ( B ) box plot of the PINP/PIIINP ratio in controls and patients.

Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

Techniques: Clinical Proteomics

( A ) Scatter plots of PINP plasma concentrations and ages of healthy subjects and patients; ( B ) scatter plots of PIIINP plasma concentrations and ages of healthy subjects and patients.

Journal: International Journal of Molecular Sciences

Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

doi: 10.3390/ijms26157032

Figure Lengend Snippet: ( A ) Scatter plots of PINP plasma concentrations and ages of healthy subjects and patients; ( B ) scatter plots of PIIINP plasma concentrations and ages of healthy subjects and patients.

Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

Techniques: Clinical Proteomics

Box plots of PINP plasma concentrations and PINP/PIIINP ratio in patients with different hernia sizes. * Extreme values.

Journal: International Journal of Molecular Sciences

Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

doi: 10.3390/ijms26157032

Figure Lengend Snippet: Box plots of PINP plasma concentrations and PINP/PIIINP ratio in patients with different hernia sizes. * Extreme values.

Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

Techniques: Clinical Proteomics

ROC curve for inguinal hernia prediction based on the PINP/PIIINP ratio.

Journal: International Journal of Molecular Sciences

Article Title: Circulating Biomarkers as Potential Risk Factors for Inguinal Hernia

doi: 10.3390/ijms26157032

Figure Lengend Snippet: ROC curve for inguinal hernia prediction based on the PINP/PIIINP ratio.

Article Snippet: ELISA kits were used to estimate the plasma concentrations of LOX enzyme (MBS2704542 by MyBioSource, San Diego, CA, USA), PINP (E-EL-H0185 by Elabscience, Houston, TX, USA), PIIINP (E-EL-H0183 by Elabscience), and PIVNP (orb561684 by Biorbyt, Durham, NC, USA) following manufacturer instructions.

Techniques: