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a) Design in GDS (Graphic Design System) format used to produce photolithographic masks for the photonic chip. The overall footprint is 5.8 × 4.0 mm, with 2 banks of 7 × 2 ring resonators, each with a total diameter of 300 μm including the trench (open area in the top layer of SiO 2 allowing direct contact between the ring resonator and analyte-containing solution). One temperature control ring (under oxide) is also provided in each bank. b) A photograph of the chip after fabrication and dicing. c) Functionalization chemistry using a succinic anhydride-bearing silane. d) Photomicrograph of a ring bank, with the antibody layout superimposed. e) An image acquired by the <t>microarrayer</t> immediately after spotting shows reproducible spotting of antibody solutions and StabilGuard over the rings. The dark spots are ∼250 pL drops settled in the ring trenches.
Sx Sciflexarrayer Piezoelectric Microarrayer, supplied by SCIENION, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sx sciflexarrayer piezoelectric microarrayer/product/SCIENION
Average 95 stars, based on 1 article reviews
sx sciflexarrayer piezoelectric microarrayer - by Bioz Stars, 2026-04
95/100 stars
  Buy from Supplier

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a) Design in GDS (Graphic Design System) format used to produce photolithographic masks for the photonic chip. The overall footprint is 5.8 × 4.0 mm, with 2 banks of 7 × 2 ring resonators, each with a total diameter of 300 μm including the trench (open area in the top layer of SiO 2 allowing direct contact between the ring resonator and analyte-containing solution). One temperature control ring (under oxide) is also provided in each bank. b) A photograph of the chip after fabrication and dicing. c) Functionalization chemistry using a succinic anhydride-bearing silane. d) Photomicrograph of a ring bank, with the antibody layout superimposed. e) An image acquired by the microarrayer immediately after spotting shows reproducible spotting of antibody solutions and StabilGuard over the rings. The dark spots are ∼250 pL drops settled in the ring trenches.

Journal: bioRxiv

Article Title: A Photonic Biosensor-Integrated Tissue Chip Platform for Real-Time Sensing of Lung Epithelial Inflammatory Markers

doi: 10.1101/2022.06.21.497028

Figure Lengend Snippet: a) Design in GDS (Graphic Design System) format used to produce photolithographic masks for the photonic chip. The overall footprint is 5.8 × 4.0 mm, with 2 banks of 7 × 2 ring resonators, each with a total diameter of 300 μm including the trench (open area in the top layer of SiO 2 allowing direct contact between the ring resonator and analyte-containing solution). One temperature control ring (under oxide) is also provided in each bank. b) A photograph of the chip after fabrication and dicing. c) Functionalization chemistry using a succinic anhydride-bearing silane. d) Photomicrograph of a ring bank, with the antibody layout superimposed. e) An image acquired by the microarrayer immediately after spotting shows reproducible spotting of antibody solutions and StabilGuard over the rings. The dark spots are ∼250 pL drops settled in the ring trenches.

Article Snippet: After silanization, antibody solutions were printed on the rings using a Scienion SX SciFLEXarrayer piezoelectric microarrayer equipped with a PDC-60 capillary nozzle.

Techniques: Control