phase contrast microscope (Nikon)
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Nikon
phase contrast microscope
Phase Contrast Microscope, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 59909 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phase-contrast+microscope/Objectives/pmc13618955-88-9-11
Average 99 stars, based on 59909 article reviews
Phase Contrast Microscope, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 59909 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phase-contrast+microscope/Objectives/pmc13618955-88-9-11
Average 99 stars, based on 59909 article reviews
phase contrast microscope - by Bioz Stars,
2026-10
99/100 stars
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Cell Migration Assay:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Cell Culture:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Wound Healing Assay:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Sterility:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Transferring:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Imaging:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Gentle:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Staining:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Microscopy:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Migration:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. Incubation:Article Title: LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation Article Snippet: The cells were washed three times with SSC buffer, stained with DAPI (1:1000, Invitrogen D3571, Shanghai, China) for 10 min at room temperature, and then examined using a Article Title: Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation. Article Snippet: Resorption pits were visualized using a Article Title: Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy Article Snippet: The number of positive cells was observed under a Article Title: Supporting Information for Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage Article Snippet: Cells were fixed with 4% paraformaldehyde for 10 min. After gentle removal of non-migrated cells with a cotton swab, the migrated cells were stained with a fluorochrome-conjugated antibody against CD11b (BioLegend, 101212, 101208, clone M1I70), photographed under a Article Title: Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy. Article Snippet: Cell migration assay hct116 and ht29 cells were cultured until they reached 90% confluence in 24-well plates and subjected to a scratch assay. controlled linear scratches were created using a sterile 200 μl pipette tip, followed by imaging at 0 h and 24 h time points using Article Title: WIPF1 regulates stemness in small cell lung cancer. Article Snippet: Thereafter, the Giemsa staining was conducted, and the number of Article Title: On-site delivery of bioactive nanospheres utilizing lanthanides as crosslinkers and metastasis-inhibiting agents for breast cancer therapy. Article Snippet: Postoperative breast cancer patients face a critical 2–3-week window during which residual tumor cells are highly prone to metastasis, yet systemic therapies are often ineffective due to impaired vascularization and limited drug transport.. To address this challenge, we developed an injectable nanosphere formulation based on hyaluronic acid (HyA) crosslinked with lanthanide ions—europium (Eu) or lanthanum (La) ions—that act dually as physical crosslinkers and therapeutic agents.. This dual-function design ensures structural stability without chemical crosslinkers, while actively inhibiting cancer cell migration, invasion, and colonization. |
