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<t>Inhibition</t> of M <t>marinum</t> in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.
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<t>Inhibition</t> of M <t>marinum</t> in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.
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<t>Inhibition</t> of M <t>marinum</t> in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.
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<t>Inhibition</t> of M <t>marinum</t> in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.
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<t>Inhibition</t> of M <t>marinum</t> in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.
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<t>Inhibition</t> of M <t>marinum</t> in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.
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Inhibition of M marinum in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.

Journal: Bioinformatics and Biology Insights

Article Title: Computational and Experimental Characterization of Mycobacterium marinum β-Carbonic Anhydrase Inhibitors

doi: 10.1177/11779322261427120

Figure Lengend Snippet: Inhibition of M marinum in culture by the identified compounds and/or rifampicin. Panel A shows the growth inhibition of M marinum by compound F10111367, while Panel B depicts its effect in combination with rifampicin. Panel C illustrates the inhibition of M marinum by compound F26860257, and Panel D shows the synergistic effect when F26860257 is combined with rifampicin. Growth inhibition was evaluated across multiple compound concentrations over time; MIC values were not formally determined.

Article Snippet: A bioluminescence-cassette ( pMV306hsp + LuxG13 ) expressing M marinum (ATCC 927, Mmr) strain was used for the inhibition studies.

Techniques: Inhibition