Journal: Bioengineering

Article Title: The Effect of Thigh Muscle Forces on Knee Contact Force in Female Patients with Severe Knee Osteoarthritis

doi: 10.3390/bioengineering11121299

Figure Lengend Snippet: MATLAB was utilized for the initial processing of experimental data, encompassing marker trajectories, ground reaction forces (GRFs), and electromyography (EMG) signals. This processing involved filtering, normalizing EMG signals, and converting the data for compatibility with OpenSim. Utilizing OpenSim’s APIs, we scaled the model and performed inverse kinematic analysis, muscle analysis, and inverse dynamics analysis to ascertain muscle–tendon unit (MTU) lengths, moment arms, and joint moments. Muscle parameters were anthropometrically adjusted and integrated into the CEINMS calibration procedure to enhance parameter accuracy, thereby reducing the difference between experimental and predicted joint moments. Ultrasound data was employed to calibrate the maximum isometric force. By integrating two distinct neural control algorithms with varying levels of muscle parameter calibration, we ultimately developed four unique models. The CEINMS execution module utilized the refined muscle activation data, in conjunction with MTU lengths and moment arms from OpenSim, to estimate MTU forces and joint moments from individual experimental trials.

Article Snippet: Utilizing OpenSim’s APIs, we scaled the model and performed inverse kinematic analysis, muscle analysis, and inverse dynamics analysis to ascertain muscle–tendon unit (MTU) lengths, moment arms, and joint moments.

Techniques: Marker, Control, Activation Assay