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Vancomycin PPK model studies in adult patients by the nonlinear mixed-effects modeling method.

Journal: Scientific Reports

Article Title: Population pharmacokinetic modeling and clinical application of vancomycin in Chinese patients hospitalized in intensive care units

doi: 10.1038/s41598-021-82312-2

Figure Lengend Snippet: Vancomycin PPK model studies in adult patients by the nonlinear mixed-effects modeling method.

Article Snippet: Population pharmacokinetic analysis was performed with 993 serum concentrations versus time from 374 adult patients (294 for model building and 80 for external validation, randomly selected by Kinetica), using a nonlinear mixed-effects modeling method with Kinetica.

Techniques: