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<t> Sequencing </t> statistics for calculating enrichment ratios of the different panning samples. For each data set the total number of sequencing reads, the number of reads that passed quality control and further processing, as well as the number of observed versus the expected number of single NNK mutations in all three CDRs of given sample are listed.
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<t> Sequencing </t> statistics for calculating enrichment ratios of the different panning samples. For each data set the total number of sequencing reads, the number of reads that passed quality control and further processing, as well as the number of observed versus the expected number of single NNK mutations in all three CDRs of given sample are listed.
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Sequencing statistics for calculating enrichment ratios of the different panning samples. For each data set the total number of sequencing reads, the number of reads that passed quality control and further processing, as well as the number of observed versus the expected number of single NNK mutations in all three CDRs of given sample are listed.

Journal: mAbs

Article Title: Tuning the specificity of a Two-in-One Fab against three angiogenic antigens by fully utilizing the information of deep mutational scanning

doi: 10.1080/19420862.2017.1337618

Figure Lengend Snippet: Sequencing statistics for calculating enrichment ratios of the different panning samples. For each data set the total number of sequencing reads, the number of reads that passed quality control and further processing, as well as the number of observed versus the expected number of single NNK mutations in all three CDRs of given sample are listed.

Article Snippet: 15,19 Recently, a new approach called deep mutational scanning, which adds deep sequencing (or NextGen Sequencing) to the combination of single- or multiple-site saturated mutagenesis libraries and a selection by a display system, has enabled large-scale assessment of the effects of mutations on the functional fitness of a protein, e.g., ligand binding function.

Techniques: Sequencing, Control