multitarget anticancer agents (MultiTarget Pharmaceuticals)
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Multitarget Anticancer Agents, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multitarget+anticancer+agents/anticancer+copper+ii++multitarget+pro+drug/pm40515697-626-20-20
Average 90 stars, based on 1 article reviews
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other:Article Title: Transferrin-Modified Nanoliposome Codelivery Strategies for Enhancing the Cancer Therapy. Article Snippet: Chemotherapy remains one of most effective treatments for many cancers in clinic.. At present, various targets have been used to modify the PEGylated liposomes for doxorubicin (Dox) delivery, but anti-tumor effect of Dox is not satisfactory.. Therefore, combination chemotherapeutics has been considered as a promising method to improve tumor treatment. Article Title: Discovery of Diaryl Piperidone-Sulfonamide as a Novel Dual-Target Inhibitor of STAT3/CAIX Inducing Ferroptosis in Triple-Negative Breast Cancer Cells. Article Snippet: A series of diaryl piperidone-sulfonamide derivatives were designed as dual inhibitors of STAT3/CAIX and ferroptosis inducers for triple-negative breast cancer (TNBC).. The representative compound 7m demonstrated significant antitumor effects against the MDA-MB-231 cell line both in vitro and in vivo.. Mechanistically, 7m inhibits the phosphorylation of STAT3, with a binding affinity determined by surface plasmon resonance (SPR) analysis (KD = 60.03 ± 8.13 μM). Histone Deacetylase Assay:Article Title: Multitargeted 6-Substituted Thieno[2,3- d ]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism. Article Snippet: .. 2019, 62, 10995−11003. (22) Martínez, R.; Di Geronimo, B.; Pastor, M.; Zapico, J. M.; Coderch, C.; Panchuk, R.; Skorokhyd, N.; Maslyk, M.; Ramos, A.; de Pascual-Teresa, |
