Journal: Trends in Psychiatry and Psychotherapy

Article Title: Sleep alterations as a predictor of bipolar disorder among offspring of parents with bipolar disorder: a systematic review and meta-analysis

doi: 10.47626/2237-6089-2021-0256

Figure Lengend Snippet: Overview of included studies in the systematic review

Article Snippet: Sebela et al., 11 2017, Czech Republic , To extend the knowledge of sleep characteristics in offspring at risk for BD , Cross-sectional , 42 BO (mean age 12.5±3.2) and 42 sex and age matched comparison CO , 5 cases of bipolar spectrum disorders and 6 cases of depressive spectrum disorders were found in the BO group No cases of bipolar spectrum disorders or depressive spectrum disorders were found in the control group , SADS – Lifetime version (SADS-L) , Kiddie SADS – Present and Lifetime version (KSADS-PL) , Actigraphic device (MotionWatch8, CamNTech, Cambridge, UK) for 14 days MEQ to assess circadian preference PSQ for investigation of childhood sleep related breathing disorders and prominent symptom complexes GBI – Sleep Subscale was used to assess sleep disturbances typical for BD , The subjective BO assessment found increased sleep and average insomnia, regardless of mood and energy levels, and depressed mood with insomnia at the beginning of sleep. In the analysis of the separate items, the BO reported significant worsening in the item depressed mood with insomnia at the beginning. The actigraphic results found a longer sleep latency among BO compared to CO , Yes , 8/9.

Techniques: Biomarker Discovery, Control, Selection, Activity Assay, Comparison, Modification, Standard Deviation