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Endophytic antifungal natural products with their potential activity against Candida albicans, C. auris, Cryptococcus neoformans and Aspergillus fumigatus

Journal: Microbial Cell Factories

Article Title: The limitless endophytes: their role as antifungal agents against top priority pathogens

doi: 10.1186/s12934-024-02411-3

Figure Lengend Snippet: Endophytic antifungal natural products with their potential activity against Candida albicans, C. auris, Cryptococcus neoformans and Aspergillus fumigatus

Article Snippet: 225 , Mycorrhizin A , Benzofuran , Viburnum tinus , Pezicula sp. , Cytotoxic, moderate anticandidal effect MIC = 66.6 μg/mL, active against Bacillus subtilis DSM 10, Chromobacterium violaceum DSM 30191, Mycobacterium smegmatis ATCC 700084, Staphylococcus aureu s DSM 346, Mucor hiemalis DSM 2656, Pichia anomala DSM 6766, Rhodotorula glutinis DSM 10134, Schizosaccharomyces pombe DSM 70572 MIC between 4.2 and 66 μg/mL , [ ] .

Techniques: Activity Assay, Inhibition, In Vitro, Sterility, Positive Control

Antibiogram representing the antibacterial activity of moscatilin toward the Gram-positive and Gram-negative bacterial pathogens under investigation. ( A ) S. aureus ; ( B ) S. epidermidis ; ( C ) B. subtilis ; ( D ) E. coli ; (E ) K. pneumonia ; ( F ) P. aeruginosa. Numbers and abbreviations inside each Petri dish denote: ( 1 ) 400 μM; ( 2 ) 200 μM; ( 3 ) 100 μM; ( 4 ) 50 μM; (-ve ) negative control, PBS; ( +ve ) chloramphenicol (25 μg/mL) positive control.

Journal: Heliyon

Article Title: Evaluation of the anticancer and antibacterial activities of moscatilin

doi: 10.1016/j.heliyon.2024.e31131

Figure Lengend Snippet: Antibiogram representing the antibacterial activity of moscatilin toward the Gram-positive and Gram-negative bacterial pathogens under investigation. ( A ) S. aureus ; ( B ) S. epidermidis ; ( C ) B. subtilis ; ( D ) E. coli ; (E ) K. pneumonia ; ( F ) P. aeruginosa. Numbers and abbreviations inside each Petri dish denote: ( 1 ) 400 μM; ( 2 ) 200 μM; ( 3 ) 100 μM; ( 4 ) 50 μM; (-ve ) negative control, PBS; ( +ve ) chloramphenicol (25 μg/mL) positive control.

Article Snippet: It was also observed that moscatilin possessed potent antibacterial effects against S. epidermidis (ATCC 12228) and K. pneumonia (ATCC 13883), moderate antibacterial effects against S. aureus (ATCC 29213) and B. subtilis (ATCC 10400), and weak antibacterial effects against E. coli (ATCC 25922) and P. aeruginosa (ATCC 27853) ( , , ).

Techniques: Activity Assay, Negative Control, Positive Control