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Associations of metabolite modules with coagulation markers. ACT: activated clotting time; aPTT: activated partial thromboplastin time; INR: international normalized ratio; PT: prothrombin time

Journal: medRxiv

Article Title: Novel Metabolites Are Associated with Coagulation Markers in Children with Congenital Heart Disease: A Metabolomic Study

doi: 10.1101/2025.11.07.25339794

Figure Lengend Snippet: Associations of metabolite modules with coagulation markers. ACT: activated clotting time; aPTT: activated partial thromboplastin time; INR: international normalized ratio; PT: prothrombin time

Article Snippet: Metabolon applied several procedures to the raw metabolite data: first, the data were batch-adjusted by scaling raw metabolite levels to have a within-batch median of 1, then missing data were imputed to the median, and finally a log transformation was applied.

Techniques: Coagulation