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ATCC
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ATCC
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Thermo Fisher
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Aladdin Co Ltd
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Elixirgen Scientific
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Macklin Inc
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Charles River Laboratories
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Creative Bioarray Inc
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Nacalai
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Gelest Inc
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Journal: Neoplasia (New York, N.Y.)
Article Title: PIK3CA mutant cervical cancer is selectively suppressed by PI3Kα inhibition (Alpelisib/BYL-719 and Inavolisib/GDC-0077) and cooperates with HPV directed T cell therapy
doi: 10.1016/j.neo.2026.101305
Figure Lengend Snippet: Impact of BYL-719 on the expression of target proteins in cervical cancer cell lines. ( A, B) CaSki cells treated with BYL-719 show reduced levels of PD-L1, YAP1, EGFR, CTGF, Integrin, and HPV16 E7. In Panel B cells were treated with 5uM BYL-719, washed at 24 h and place in 0, 1 or 5uM drug. (exposure time, 2 min). (C) BYL-719-treated ME180 cells show decreased levels of PD-L1 and CTGF. (D) SNU-17 cells also show reduced levels of these proteins after treatment (exposure time, 5 min). (E) SiHa ( PIK3CA WT) shows no reduction ofHPV16 E7 after treatment with BYL-719 (exposure time, 3 min). (F) Cell proliferation plot of SNU-17 cells treated with BYL-719. (G) SiHa cells treated with BYL719. *=P < 0.05, **=P < 0.01, ***=P < 0.001.
Article Snippet: CC cell lines, including CaSki (ATCC Cat# CRM-CRL-1550_Ca Ski, RRID: CVCL_1100), SiHa (ATCC Cat# HTB-35_SiHa, RRID: CVCL_0032), and
Techniques: Expressing
Journal: bioRxiv
Article Title: Identification of non-covalent inhibitors for the atypical peroxiredoxin PRDX5 as a therapeutic strategy in malignant pleural mesothelioma
doi: 10.64898/2026.05.13.724787
Figure Lengend Snippet: A. IST-MES-1, IST-MES-2, MSTO-211H and MeT-5A cells were incubated for 5 days in presence of exogenous Peroxynitrite (left panel) or H 2 O 2 (right panel) at different concentrations. Cell viability was measured using CellTiter assay (luminescence). B. Digital representation of data obtained for PRDX3 and PRDX5 detection (capillary western blot) in cell line panel (left panel). Bar plots showing data from one individual run (2 replicates per condition, SD value, right panel).
Article Snippet: The human malignant pleural mesothelioma (MPM) cell lines IST-MES-1, and
Techniques: Incubation, Western Blot