Review





Similar Products

quantum gx2 mct imaging system  (Revvity)
97
Revvity quantum gx2 mct imaging system
Quantum Gx2 Mct Imaging System, supplied by Revvity, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/quantum gx2 mct imaging system/product/Revvity
Average 97 stars, based on 1 article reviews
quantum gx2 mct imaging system - by Bioz Stars, 2026-04
97/100 stars
  Buy from Supplier
mct administration  (MedChemExpress)
95
MedChemExpress mct administration
Mct Administration, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mct administration/product/MedChemExpress
Average 95 stars, based on 1 article reviews
mct administration - by Bioz Stars, 2026-04
95/100 stars
  Buy from Supplier
mercury cadmium telluride mct detector  (Bruker Corporation)
99
Bruker Corporation mercury cadmium telluride mct detector
Mercury Cadmium Telluride Mct Detector, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mercury cadmium telluride mct detector/product/Bruker Corporation
Average 99 stars, based on 1 article reviews
mercury cadmium telluride mct detector - by Bioz Stars, 2026-04
99/100 stars
  Buy from Supplier
nitrogen cooled mct detector  (Bruker Corporation)
99
Bruker Corporation nitrogen cooled mct detector
Nitrogen Cooled Mct Detector, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nitrogen cooled mct detector/product/Bruker Corporation
Average 99 stars, based on 1 article reviews
nitrogen cooled mct detector - by Bioz Stars, 2026-04
99/100 stars
  Buy from Supplier
primary antibodies against mct 1  (Proteintech)
96
Proteintech primary antibodies against mct 1
Primary Antibodies Against Mct 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/primary antibodies against mct 1/product/Proteintech
Average 96 stars, based on 1 article reviews
primary antibodies against mct 1 - by Bioz Stars, 2026-04
96/100 stars
  Buy from Supplier
mouse mast cell tryptase elisa kit  (Cusabio)
93
Cusabio mouse mast cell tryptase elisa kit
Mast cell stabilizer prevents mast cell degranulation and reduces sprouting. (A) Day 8 representative explant images showing choroidal sprouting under the indicated conditions. Yellow outline indicates sprouting area, center black outline indicates explant. (B) Time-course analysis of choroidal sprouting in explants treated with mast cell degranulator (48/80) in the presence or absence of the KF. 48/80 was applied on days 2, 4, and 6 (arrows marked “T”) alongside KF. Significant differences in sprouting were observed at 4, 6 and 8 days. (C, D) Quantification of sprouting in WT explants treated with 48/80 +/- KF or just KF vs control shows significantly more sprouting when the mast cell degranulator is not present. (N=3). <t>(E)</t> <t>Tryptase</t> <t>ELISA</t> on CSA supernatants from indicated conditions. 48/80 treated explant supernatants contain significantly more tryptase than KF treated supernatant samples. (N=3). (F) Bleached CSA choroids stained with Toluidine blue after the treatments indicated. Arrows point to mast cells (or degranulated mast cells). Scale bar represents 20µm. Data are presented as mean ± SEM. N = 3 per condition. Statistical analysis was performed using unpaired t-tests. *p<0.05, **p<0.01, ***p<0.001, ns = not significant.
Mouse Mast Cell Tryptase Elisa Kit, supplied by Cusabio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse mast cell tryptase elisa kit/product/Cusabio
Average 93 stars, based on 1 article reviews
mouse mast cell tryptase elisa kit - by Bioz Stars, 2026-04
93/100 stars
  Buy from Supplier
mct ro 3306 group  (MedChemExpress)
96
MedChemExpress mct ro 3306 group
Mast cell stabilizer prevents mast cell degranulation and reduces sprouting. (A) Day 8 representative explant images showing choroidal sprouting under the indicated conditions. Yellow outline indicates sprouting area, center black outline indicates explant. (B) Time-course analysis of choroidal sprouting in explants treated with mast cell degranulator (48/80) in the presence or absence of the KF. 48/80 was applied on days 2, 4, and 6 (arrows marked “T”) alongside KF. Significant differences in sprouting were observed at 4, 6 and 8 days. (C, D) Quantification of sprouting in WT explants treated with 48/80 +/- KF or just KF vs control shows significantly more sprouting when the mast cell degranulator is not present. (N=3). <t>(E)</t> <t>Tryptase</t> <t>ELISA</t> on CSA supernatants from indicated conditions. 48/80 treated explant supernatants contain significantly more tryptase than KF treated supernatant samples. (N=3). (F) Bleached CSA choroids stained with Toluidine blue after the treatments indicated. Arrows point to mast cells (or degranulated mast cells). Scale bar represents 20µm. Data are presented as mean ± SEM. N = 3 per condition. Statistical analysis was performed using unpaired t-tests. *p<0.05, **p<0.01, ***p<0.001, ns = not significant.
Mct Ro 3306 Group, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mct ro 3306 group/product/MedChemExpress
Average 96 stars, based on 1 article reviews
mct ro 3306 group - by Bioz Stars, 2026-04
96/100 stars
  Buy from Supplier
mct ro3306 group  (MedChemExpress)
96
MedChemExpress mct ro3306 group
Mast cell stabilizer prevents mast cell degranulation and reduces sprouting. (A) Day 8 representative explant images showing choroidal sprouting under the indicated conditions. Yellow outline indicates sprouting area, center black outline indicates explant. (B) Time-course analysis of choroidal sprouting in explants treated with mast cell degranulator (48/80) in the presence or absence of the KF. 48/80 was applied on days 2, 4, and 6 (arrows marked “T”) alongside KF. Significant differences in sprouting were observed at 4, 6 and 8 days. (C, D) Quantification of sprouting in WT explants treated with 48/80 +/- KF or just KF vs control shows significantly more sprouting when the mast cell degranulator is not present. (N=3). <t>(E)</t> <t>Tryptase</t> <t>ELISA</t> on CSA supernatants from indicated conditions. 48/80 treated explant supernatants contain significantly more tryptase than KF treated supernatant samples. (N=3). (F) Bleached CSA choroids stained with Toluidine blue after the treatments indicated. Arrows point to mast cells (or degranulated mast cells). Scale bar represents 20µm. Data are presented as mean ± SEM. N = 3 per condition. Statistical analysis was performed using unpaired t-tests. *p<0.05, **p<0.01, ***p<0.001, ns = not significant.
Mct Ro3306 Group, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mct ro3306 group/product/MedChemExpress
Average 96 stars, based on 1 article reviews
mct ro3306 group - by Bioz Stars, 2026-04
96/100 stars
  Buy from Supplier

Image Search Results


Mast cell stabilizer prevents mast cell degranulation and reduces sprouting. (A) Day 8 representative explant images showing choroidal sprouting under the indicated conditions. Yellow outline indicates sprouting area, center black outline indicates explant. (B) Time-course analysis of choroidal sprouting in explants treated with mast cell degranulator (48/80) in the presence or absence of the KF. 48/80 was applied on days 2, 4, and 6 (arrows marked “T”) alongside KF. Significant differences in sprouting were observed at 4, 6 and 8 days. (C, D) Quantification of sprouting in WT explants treated with 48/80 +/- KF or just KF vs control shows significantly more sprouting when the mast cell degranulator is not present. (N=3). (E) Tryptase ELISA on CSA supernatants from indicated conditions. 48/80 treated explant supernatants contain significantly more tryptase than KF treated supernatant samples. (N=3). (F) Bleached CSA choroids stained with Toluidine blue after the treatments indicated. Arrows point to mast cells (or degranulated mast cells). Scale bar represents 20µm. Data are presented as mean ± SEM. N = 3 per condition. Statistical analysis was performed using unpaired t-tests. *p<0.05, **p<0.01, ***p<0.001, ns = not significant.

Journal: Frontiers in Immunology

Article Title: Granzyme B from mast cells contributes to choroidal neovascularization in a model of wet age-related macular degeneration

doi: 10.3389/fimmu.2026.1710965

Figure Lengend Snippet: Mast cell stabilizer prevents mast cell degranulation and reduces sprouting. (A) Day 8 representative explant images showing choroidal sprouting under the indicated conditions. Yellow outline indicates sprouting area, center black outline indicates explant. (B) Time-course analysis of choroidal sprouting in explants treated with mast cell degranulator (48/80) in the presence or absence of the KF. 48/80 was applied on days 2, 4, and 6 (arrows marked “T”) alongside KF. Significant differences in sprouting were observed at 4, 6 and 8 days. (C, D) Quantification of sprouting in WT explants treated with 48/80 +/- KF or just KF vs control shows significantly more sprouting when the mast cell degranulator is not present. (N=3). (E) Tryptase ELISA on CSA supernatants from indicated conditions. 48/80 treated explant supernatants contain significantly more tryptase than KF treated supernatant samples. (N=3). (F) Bleached CSA choroids stained with Toluidine blue after the treatments indicated. Arrows point to mast cells (or degranulated mast cells). Scale bar represents 20µm. Data are presented as mean ± SEM. N = 3 per condition. Statistical analysis was performed using unpaired t-tests. *p<0.05, **p<0.01, ***p<0.001, ns = not significant.

Article Snippet: Using the Mouse Mast Cell Tryptase ELISA Kit (CUSABIO, Cat. CSB-E14326m-1), supernatants were added neat into wells and incubated for 1 hour at 37 °C.

Techniques: Control, Enzyme-linked Immunosorbent Assay, Staining