Review





Similar Products

lipid contents  (MedChemExpress)
99
MedChemExpress lipid contents
Lipid Contents, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/BODIPY+493%2F503/pm42310288-122-3-18
Average 99 stars, based on 1 article reviews
lipid contents - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier
lipid content  (Macklin Inc)
86
Macklin Inc lipid content
Lipid Content, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/content+lipid/pm42280692-149-5-8
Average 86 stars, based on 1 article reviews
lipid content - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier
ionizable lipid content influences mrna lnp characteristics  (Moderna)
86
Moderna ionizable lipid content influences mrna lnp characteristics
Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment <t>with</t> <t>mRNA-LNP</t> for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001
Ionizable Lipid Content Influences Mrna Lnp Characteristics, supplied by Moderna, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/lnp+mrna+solution/pmc13200424-33-3-19
Average 86 stars, based on 1 article reviews
ionizable lipid content influences mrna lnp characteristics - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier
lipid content  (MedChemExpress)
99
MedChemExpress lipid content
Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment <t>with</t> <t>mRNA-LNP</t> for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001
Lipid Content, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/BODIPY+493%2F503/pmc13047273-370-0-7
Average 99 stars, based on 1 article reviews
lipid content - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier
lipid peroxidation lpo content  (Nanjing Jiancheng Bioengineering Research Institute Co Ltd)
86
Nanjing Jiancheng Bioengineering Research Institute Co Ltd lipid peroxidation lpo content
Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment <t>with</t> <t>mRNA-LNP</t> for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001
Lipid Peroxidation Lpo Content, supplied by Nanjing Jiancheng Bioengineering Research Institute Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/assay+kit+ros/pm41899005-138-6-26
Average 86 stars, based on 1 article reviews
lipid peroxidation lpo content - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier
mda content mda detection kit  (Beyotime)
99
Beyotime mda content mda detection kit
Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment <t>with</t> <t>mRNA-LNP</t> for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001
Mda Content Mda Detection Kit, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/Lipid+Peroxidation+MDA+Assay+Kit/pm41404869-65-8-13
Average 99 stars, based on 1 article reviews
mda content mda detection kit - by Bioz Stars, 2026-10
99/100 stars
  Buy from Supplier
peg lipid content  (Pfizer Inc)
86
Pfizer Inc peg lipid content
Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment <t>with</t> <t>mRNA-LNP</t> for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001
Peg Lipid Content, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/content+lipid+peg/pmc12388858-165-24-20
Average 86 stars, based on 1 article reviews
peg lipid content - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier
lipid content analysis  (AXYS Analytical Services Ltd)
90
AXYS Analytical Services Ltd lipid content analysis
Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment <t>with</t> <t>mRNA-LNP</t> for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001
Lipid Content Analysis, supplied by AXYS Analytical Services Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lipids+contents/lipid+content+analysis/pm40613683-61-9-13
Average 90 stars, based on 1 article reviews
lipid content analysis - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment with mRNA-LNP for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001

Journal: Journal of Nanobiotechnology

Article Title: Mechanistic insights into mRNA–LNP interactions: role of ionizable lipid content in regulating mRNA intracellular release and translation

doi: 10.1186/s12951-026-04383-5

Figure Lengend Snippet: Intracellular dissociation of mRNA from LNPs. ( a ) Representative confocal images of HEK293 cells after treatment with mRNA-LNP for 6 h: dual-labeled mRNA-LNPs: NBD-cholesterol for LNPs (green) and Cy5 for mRNA (red). Nuclei were stained with Hoechst 33,342 (blue). Scale bars, 25 μm. ( b ) Quantification of intracellular LNP and mRNA colocalization based on 7–10 images for each group, expressed as Pearson’s correlation coefficient and analyzed using ImageJ. Data are presented as mean ± SD. *** p < 0.001

Article Snippet: To investigate how ionizable lipid content influences mRNA-LNP characteristics, we started with benchmark formulations based on the clinically approved Moderna and Pfizer/BioNTech mRNA-LNP formulation.

Techniques: Labeling, Staining