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laboras test boxes  (Metris Therapeutics)
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Metris Therapeutics laboras test boxes
Overview of experiments and mice used for the respective experiments.
Laboras Test Boxes, supplied by Metris Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/laboras+test+boxes/laboras+test+boxes/pmc11532339-43-5-29
Average 90 stars, based on 1 article reviews
laboras test boxes - by Bioz Stars, 2026-09
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Overview of experiments and mice used for the respective experiments.

Journal: Scientific Reports

Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

doi: 10.1038/s41598-024-78332-3

Figure Lengend Snippet: Overview of experiments and mice used for the respective experiments.

Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

Techniques: Biomarker Discovery

Schematic overview of experimental protocols and setup for each experiment. ( A ) Graphic illustration of timeline and study design for experiment 1–3. ( B ) Picture of LABORAS test cages. ( C ) Picture of burrowing tube in test cage. NB. Pictures do not represent the experimental light conditions. Created with BioRender.com.

Journal: Scientific Reports

Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

doi: 10.1038/s41598-024-78332-3

Figure Lengend Snippet: Schematic overview of experimental protocols and setup for each experiment. ( A ) Graphic illustration of timeline and study design for experiment 1–3. ( B ) Picture of LABORAS test cages. ( C ) Picture of burrowing tube in test cage. NB. Pictures do not represent the experimental light conditions. Created with BioRender.com.

Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

Techniques:

Data summary from Experiment 1 and 2. A) Von Frey test was performed before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 16/group, individual values and mean ± SEM. B-D) 4 h LABORAS data obtained from same mice as in A on days 1, 5, 7, and 9 immediately after GTN injection. No effect of GTN, but increased activity when testing during the dark phase (day 5), day effect p < 0.0001, Two-way repeated ANOVA. E-F) Von Frey data days 1–9 before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 12/group, mean ± SEM. G-H) Locomotion and distance traveled on day 11 with a 60 min delay of LABORAS initiation after GTN injection. Same mice as in E-F, students t-test.

Journal: Scientific Reports

Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

doi: 10.1038/s41598-024-78332-3

Figure Lengend Snippet: Data summary from Experiment 1 and 2. A) Von Frey test was performed before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 16/group, individual values and mean ± SEM. B-D) 4 h LABORAS data obtained from same mice as in A on days 1, 5, 7, and 9 immediately after GTN injection. No effect of GTN, but increased activity when testing during the dark phase (day 5), day effect p < 0.0001, Two-way repeated ANOVA. E-F) Von Frey data days 1–9 before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 12/group, mean ± SEM. G-H) Locomotion and distance traveled on day 11 with a 60 min delay of LABORAS initiation after GTN injection. Same mice as in E-F, students t-test.

Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

Techniques: Injection, Comparison, Activity Assay