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Journal: bioRxiv

Article Title: The c-Src inhibitor eCF506 diminishes opioid tolerance creating bias against β-arrestin2 recruitment

doi: 10.1101/2025.07.01.662507

Figure Lengend Snippet:

Article Snippet: All constructs are based on human c-Src WT (1-536) c-Src (plasmid #42202; RRID: Addgene_42202), c-terminus truncated (1-249) c-Src (plasmid #42204; RRID: Addgene_42204), n-terminus truncated (250-536) c-Src (plasmid #42208; RRID: Addgene_42208), and kinase dead (K298M) c-Src (plasmid #42210; RRID: Addgene_42210), were donated by Dr Robert Lefkowitz.

Techniques: Mutagenesis, Concentration Assay, Over Expression, Functional Assay