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Genes altered following oxythioquinox exposure. Table represents data mined from HuGeneFL <t> microarrays </t> (Affymetrix). All genes selected have a signal log ratio of ± 0.6 unless otherwise noted. Representative genes for each group were selected based on their function and are shown here.
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Genes altered following oxythioquinox exposure. Table represents data mined from HuGeneFL microarrays (Affymetrix). All genes selected have a signal log ratio of ± 0.6 unless otherwise noted. Representative genes for each group were selected based on their function and are shown here.

Journal: Environmental Health

Article Title: The effect of oxythioquinox exposure on normal human mammary epithelial cell gene expression: A microarray analysis study

doi: 10.1186/1476-069X-3-9

Figure Lengend Snippet: Genes altered following oxythioquinox exposure. Table represents data mined from HuGeneFL microarrays (Affymetrix). All genes selected have a signal log ratio of ± 0.6 unless otherwise noted. Representative genes for each group were selected based on their function and are shown here.

Article Snippet: Gene transcription in each cell strain was analyzed using high-density oligonucleotide DNA microarrays (HuGeneFL, Affymetrix™) and changes in the expression of selected genes were verified by real-time polymerase chain reaction at extended time points (ABI).

Techniques: Transduction, Activity Assay, Permeability

Expression pattern for CYP2A13. DNA microarray analysis of NHMEC strains. Analysis was performed as described on HuGeneFL high-density oligonucleotide microarrays (Affymetrix). Results are plotted as duration of exposure vs signal log ratio (SLR). Signal log ratio is a measure of comparative expression of the treatment vs. vehicle control (0.001% DMSO). Signal log ratio of one is equal to a fold change of two. A SLR of 0.6 (Fold Change ~1.5) was the arbitrary limit of our analysis. All genes given an Absent call by analysis software are shown with a SLR of zero. Asterisks indicate a statistically significant variation in expression from the control level as measured by Tukey's Biweight analysis.

Journal: Environmental Health

Article Title: The effect of oxythioquinox exposure on normal human mammary epithelial cell gene expression: A microarray analysis study

doi: 10.1186/1476-069X-3-9

Figure Lengend Snippet: Expression pattern for CYP2A13. DNA microarray analysis of NHMEC strains. Analysis was performed as described on HuGeneFL high-density oligonucleotide microarrays (Affymetrix). Results are plotted as duration of exposure vs signal log ratio (SLR). Signal log ratio is a measure of comparative expression of the treatment vs. vehicle control (0.001% DMSO). Signal log ratio of one is equal to a fold change of two. A SLR of 0.6 (Fold Change ~1.5) was the arbitrary limit of our analysis. All genes given an Absent call by analysis software are shown with a SLR of zero. Asterisks indicate a statistically significant variation in expression from the control level as measured by Tukey's Biweight analysis.

Article Snippet: Gene transcription in each cell strain was analyzed using high-density oligonucleotide DNA microarrays (HuGeneFL, Affymetrix™) and changes in the expression of selected genes were verified by real-time polymerase chain reaction at extended time points (ABI).

Techniques: Expressing, Microarray, Software

Expression pattern for dihydrodiol dehydrogenase. DNA Microarray analysis of NHMEC strains. Analysis was performed as described on HuGeneFL high-density oligonucleotide microarrays (Affymetrix). Results are plotted as duration of exposure vs signal log ratio (SLR). Signal log ratio is a measure of comparative expression of the treatment vs. vehicle control (0.001% DMSO). Signal log ratio of one is equal to a fold change of two. A SLR of 0.6 (Fold Change ~1.5) was the arbitrary limit of our analysis. All genes given an Absent call by analysis software are shown with a SLR of zero. Asterisks indicate a statistically significant variation in expression from the control level as measured by Tukey's Biweight analysis.

Journal: Environmental Health

Article Title: The effect of oxythioquinox exposure on normal human mammary epithelial cell gene expression: A microarray analysis study

doi: 10.1186/1476-069X-3-9

Figure Lengend Snippet: Expression pattern for dihydrodiol dehydrogenase. DNA Microarray analysis of NHMEC strains. Analysis was performed as described on HuGeneFL high-density oligonucleotide microarrays (Affymetrix). Results are plotted as duration of exposure vs signal log ratio (SLR). Signal log ratio is a measure of comparative expression of the treatment vs. vehicle control (0.001% DMSO). Signal log ratio of one is equal to a fold change of two. A SLR of 0.6 (Fold Change ~1.5) was the arbitrary limit of our analysis. All genes given an Absent call by analysis software are shown with a SLR of zero. Asterisks indicate a statistically significant variation in expression from the control level as measured by Tukey's Biweight analysis.

Article Snippet: Gene transcription in each cell strain was analyzed using high-density oligonucleotide DNA microarrays (HuGeneFL, Affymetrix™) and changes in the expression of selected genes were verified by real-time polymerase chain reaction at extended time points (ABI).

Techniques: Expressing, Microarray, Software