Journal: Stem cell research & therapy

Article Title: The characteristics and medical applications of antler stem cells.

doi: 10.1186/s13287-023-03456-8

Figure Lengend Snippet: Fig. 3 Effect of ASC-CM on wound healing. A Effect of ASC-CM versus the control (DMEM, EGF, and MSC-CM) on wound healing speed. The ASC-CM group had the fastest healing rate, which was completed by day 16. B Effect of ASC-CM vs. control (DMEM, EGF, and MSC-CM) on wound healing quality. The group that received ASC-CM had the thickest dermis, the most skin appendages, the most α-SMA positive vessels, and the least number of PCNA positive cells; Reproduced with permission from [76]. © 2019 Xiaoli Rong et al. ASC-CM, antler stem cell-conditioned medium; MSC-CM, mesenchymal stem cell-conditioned medium; EGF, epidermal growth factor; α-SMA, anti-α smooth muscle actin; PCNA, proliferating cell nuclear antigen; DMEM, Dulbecco’s modified eagle medium; HE, Hematoxylin and eosin staining

Article Snippet: EV Extracellular vesicle Wnt Wingless-related integration site MSC-CM Mesenchymal stem cell-conditioned medium EGF Epidermal growth factor α-SMA Anti-α smooth muscle actin PCNA Proliferating cell nuclear antigen DMEM Dulbecco’s modified eagle medium HE Hematoxylin and eosin staining VEGF Vascular endothelial growth factor TMSB10 Thymosin β10 Exo Exosome OA Osteoarthritis Veh Vehicle α-SMA Anti-α smooth muscle actin TGF-β Transforming growth factor-β HSC Hepatic stellate cells CCl4 Carbon tetrachloride SFM Serum-free medium PBS Phosphate-buffered saline FGF Fibroblast growth factor KGF Keratinocyte growth factor TLR2/4 F Toll-like receptor 2/4 Acknowledgements We would like to thank KetengEdit (www. keten gedit. com) for linguistic assistance in the preparation of this manuscript.

Techniques: Control, Modification, Staining