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CDX2 levels in colorectal cancer cells (a) CDX2 mRNA levels in colorectal cancer (HT29, Caco2, LoVo, LS174T, and SW480), normal fibroblast <t>(HEL299),</t> and rhabdomyosarcoma (RH30) cells by RT‐PCR. P value is compared to RH30. (b) CDX2 mRNA levels in colorectal cancer cells after 5‐fluorouracil (5FU) exposure (4 days). (c) CDX2 mRNA levels in 5FU‐resistant HT29 and LS174T cells. (d) MDR1 mRNA levels in 5FU‐resistant HT29 and LS174T cells. Results are presented as mean ± SD ( n = 5). * p < 0.05 (paired t ‐test; two‐tailed).
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CDX2 levels in colorectal cancer cells (a) CDX2 mRNA levels in colorectal cancer (HT29, Caco2, LoVo, LS174T, and SW480), normal fibroblast <t>(HEL299),</t> and rhabdomyosarcoma (RH30) cells by RT‐PCR. P value is compared to RH30. (b) CDX2 mRNA levels in colorectal cancer cells after 5‐fluorouracil (5FU) exposure (4 days). (c) CDX2 mRNA levels in 5FU‐resistant HT29 and LS174T cells. (d) MDR1 mRNA levels in 5FU‐resistant HT29 and LS174T cells. Results are presented as mean ± SD ( n = 5). * p < 0.05 (paired t ‐test; two‐tailed).
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CDX2 levels in colorectal cancer cells (a) CDX2 mRNA levels in colorectal cancer (HT29, Caco2, LoVo, LS174T, and SW480), normal fibroblast (HEL299), and rhabdomyosarcoma (RH30) cells by RT‐PCR. P value is compared to RH30. (b) CDX2 mRNA levels in colorectal cancer cells after 5‐fluorouracil (5FU) exposure (4 days). (c) CDX2 mRNA levels in 5FU‐resistant HT29 and LS174T cells. (d) MDR1 mRNA levels in 5FU‐resistant HT29 and LS174T cells. Results are presented as mean ± SD ( n = 5). * p < 0.05 (paired t ‐test; two‐tailed).

Journal: Cancer Science

Article Title: CDX2 Promoter‐Controlled Oncolytic Adenovirus Suppresses Tumor Growth and Liver Metastasis of Colorectal Cancer

doi: 10.1111/cas.70063

Figure Lengend Snippet: CDX2 levels in colorectal cancer cells (a) CDX2 mRNA levels in colorectal cancer (HT29, Caco2, LoVo, LS174T, and SW480), normal fibroblast (HEL299), and rhabdomyosarcoma (RH30) cells by RT‐PCR. P value is compared to RH30. (b) CDX2 mRNA levels in colorectal cancer cells after 5‐fluorouracil (5FU) exposure (4 days). (c) CDX2 mRNA levels in 5FU‐resistant HT29 and LS174T cells. (d) MDR1 mRNA levels in 5FU‐resistant HT29 and LS174T cells. Results are presented as mean ± SD ( n = 5). * p < 0.05 (paired t ‐test; two‐tailed).

Article Snippet: Human colorectal cancer (HT29 (HTB‐38), Caco2 (HTB‐37), LoVo (CCL‐229), SW480 (CCL‐228), and LS174T (CL‐188)), rhabdomyosarcoma (RH30 (CRL‐2061)), and normal fibroblast (HEL299 (CCL‐137)) cell lines were purchased from ATCC (Manassas, VA, USA).

Techniques: Reverse Transcription Polymerase Chain Reaction, Two Tailed Test