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Dose-dependent cytotoxic effects of GNT and Apigenin on <t>HCC1937</t> cells evaluated by the MTT assay. ( A ) Dose–response curves showing percentage cell viability plotted against the logarithm of compound concentration (µM). ( B ) Bar graph representation of cell viability at increasing concentrations (10–400 µM) compared to control. Data are presented as mean ± SD ( n = 6)
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Dose-dependent cytotoxic effects of GNT and Apigenin on <t>HCC1937</t> cells evaluated by the MTT assay. ( A ) Dose–response curves showing percentage cell viability plotted against the logarithm of compound concentration (µM). ( B ) Bar graph representation of cell viability at increasing concentrations (10–400 µM) compared to control. Data are presented as mean ± SD ( n = 6)
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Dose-dependent cytotoxic effects of GNT and Apigenin on <t>HCC1937</t> cells evaluated by the MTT assay. ( A ) Dose–response curves showing percentage cell viability plotted against the logarithm of compound concentration (µM). ( B ) Bar graph representation of cell viability at increasing concentrations (10–400 µM) compared to control. Data are presented as mean ± SD ( n = 6)
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Dose-dependent cytotoxic effects of GNT and Apigenin on HCC1937 cells evaluated by the MTT assay. ( A ) Dose–response curves showing percentage cell viability plotted against the logarithm of compound concentration (µM). ( B ) Bar graph representation of cell viability at increasing concentrations (10–400 µM) compared to control. Data are presented as mean ± SD ( n = 6)

Journal: BMC Pharmacology & Toxicology

Article Title: Integrated in silico and in vitro evaluation of Genistein and Apigenin as dual inhibitors of PARP1 and ESR1 in breast cancer

doi: 10.1186/s40360-025-01082-z

Figure Lengend Snippet: Dose-dependent cytotoxic effects of GNT and Apigenin on HCC1937 cells evaluated by the MTT assay. ( A ) Dose–response curves showing percentage cell viability plotted against the logarithm of compound concentration (µM). ( B ) Bar graph representation of cell viability at increasing concentrations (10–400 µM) compared to control. Data are presented as mean ± SD ( n = 6)

Article Snippet: HCC1937 human triple-negative breast cancer (TNBC) cells were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA; Cat. No. CRL-2336).

Techniques: MTT Assay, Concentration Assay, Control