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ATCC paper emdb emd 36006 gsk256073 hcar2 gi complex
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Figure 7. Mechanism <t>of</t> <t>HCAR2-Gi</t> coupling (A) Structural comparison of the GSK256073- bound HCAR2-Gi complex with representative class A Gi-coupled D2R (PDB: 7JVR). (B and C) Detailed interactions between Gai and HCAR2. The polar interactions are depicted by black dashed lines. See also Figure S9.
Hcar2 Gi Complexes, supplied by TargetMol, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Figure 7. Mechanism <t>of</t> <t>HCAR2-Gi</t> coupling (A) Structural comparison of the GSK256073- bound HCAR2-Gi complex with representative class A Gi-coupled D2R (PDB: 7JVR). (B and C) Detailed interactions between Gai and HCAR2. The polar interactions are depicted by black dashed lines. See also Figure S9.
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Figure 7. Mechanism of HCAR2-Gi coupling (A) Structural comparison of the GSK256073- bound HCAR2-Gi complex with representative class A Gi-coupled D2R (PDB: 7JVR). (B and C) Detailed interactions between Gai and HCAR2. The polar interactions are depicted by black dashed lines. See also Figure S9.

Journal: Cell reports

Article Title: Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2.

doi: 10.1016/j.celrep.2023.113406

Figure Lengend Snippet: Figure 7. Mechanism of HCAR2-Gi coupling (A) Structural comparison of the GSK256073- bound HCAR2-Gi complex with representative class A Gi-coupled D2R (PDB: 7JVR). (B and C) Detailed interactions between Gai and HCAR2. The polar interactions are depicted by black dashed lines. See also Figure S9.

Article Snippet: The HCAR2-Gi complexes were formed in membranes by the addition of 40mM Niacin (TargetMol), or 20mM MK-6892 (TargetMol), or 40mM GSK256073 (TargetMol), respectively.

Techniques: Comparison