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List of Current Anti-TGFβ Therapeutic and Combined Strategies in Pre-Clinical Development

Journal: OncoTargets and Therapy

Article Title: Exploring TGF-β Signaling in Cancer Progression: Prospects and Therapeutic Strategies

doi: 10.2147/OTT.S493643

Figure Lengend Snippet: List of Current Anti-TGFβ Therapeutic and Combined Strategies in Pre-Clinical Development

Article Snippet: Fresolimumab (GC1008, Genzyme), a human monoclonal antibody, broadly neutralizes all three isoforms of TGF-β by interrupting their binding with receptors.

Techniques: Histone Deacetylase Assay, Clinical Proteomics

Agents targeting TGF-β in preclinical or clinical studies

Journal: Signal Transduction and Targeted Therapy

Article Title: Targeting cytokine and chemokine signaling pathways for cancer therapy

doi: 10.1038/s41392-024-01868-3

Figure Lengend Snippet: Agents targeting TGF-β in preclinical or clinical studies

Article Snippet: TGF-β , mAb , Fresolimumab , Genzyme.

Techniques: