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FIG. 6. <t>FLUKA</t> simulation of radial distribution of dose per primary irradiating particle in 1 lm thick cell culture layer exposed to 0.2 cGy of 1,000 MeV/u 56Fe ions. Panel A: Radial distribution of dose of 56Fe ions, heavy ions, 1 keV threshold electrons and the total dose. Panel B: Radial distribution of dose of electrons with various d ray thresholds (1, 10, 100 keV and 1 MeV). Panels C and D illustrate radial distribution of dose from heavy ions (primary and secondary) and electrons, respectively, by superimposing the radial dose area over panel D in Fig. 5, where cells traversed by a primary 56Fe ion track were identified.
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FIG. 6. FLUKA simulation of radial distribution of dose per primary irradiating particle in 1 lm thick cell culture layer exposed to 0.2 cGy of 1,000 MeV/u 56Fe ions. Panel A: Radial distribution of dose of 56Fe ions, heavy ions, 1 keV threshold electrons and the total dose. Panel B: Radial distribution of dose of electrons with various d ray thresholds (1, 10, 100 keV and 1 MeV). Panels C and D illustrate radial distribution of dose from heavy ions (primary and secondary) and electrons, respectively, by superimposing the radial dose area over panel D in Fig. 5, where cells traversed by a primary 56Fe ion track were identified.

Journal: Radiation Research

Article Title: Nontargeted Stressful Effects in Normal Human Fibroblast Cultures Exposed to Low Fluences of High Charge, High Energy (HZE) Particles: Kinetics of Biologic Responses and Significance of Secondary Radiations

doi: 10.1667/rr3017.1

Figure Lengend Snippet: FIG. 6. FLUKA simulation of radial distribution of dose per primary irradiating particle in 1 lm thick cell culture layer exposed to 0.2 cGy of 1,000 MeV/u 56Fe ions. Panel A: Radial distribution of dose of 56Fe ions, heavy ions, 1 keV threshold electrons and the total dose. Panel B: Radial distribution of dose of electrons with various d ray thresholds (1, 10, 100 keV and 1 MeV). Panels C and D illustrate radial distribution of dose from heavy ions (primary and secondary) and electrons, respectively, by superimposing the radial dose area over panel D in Fig. 5, where cells traversed by a primary 56Fe ion track were identified.

Article Snippet: Simulations with the FLUKA multi-particle transport code revealed that fragmentation products, other than electrons, in cell cultures exposed to HZE particles comprise ,1% of the absorbed dose.

Techniques: Cell Culture