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quinoline based fibroblast activation protein fap targeted tracer fapi 46  (MedChemExpress)
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MedChemExpress quinoline based fibroblast activation protein fap targeted tracer fapi 46
Quinoline Based Fibroblast Activation Protein Fap Targeted Tracer Fapi 46, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fapi 46 precursor  (MedChemExpress)
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MedChemExpress fapi 46 precursor
Representative chemical structures and functional groups of (A) FAPI-04, (B) <t>FAPI-46,</t> and (C) Alb-FAPtp-01 and (D) the developed peptide tracer (Alb-FAPtp-02). (E) FAP expression level in U-87MG and HEK293T. (F) Cellular uptake of ⁶⁸Ga-FAPI-04, ⁶⁸Ga-FAPI-46, and ⁶⁸Ga-Alb-FAPtp-02 in U-87 MG and HEK293T cells. No significant. (G) Competitive binding assay showing inhibition of tracer uptake in U-87 MG cells by non-radiolabeled FAPI-04, confirming FAP-specific binding (n = 3, mean ± s.d.). ( H ) In vivo dynamic PET imaging analysis comparison of FAP tracers. Representative dynamic PET/CT imaging of ⁶⁸Ga-Alb-FAPtp-02, ⁶⁸Ga-FAPI-46 and ⁶⁸Ga-FAPI-04 in mice with glioma xenografts. (I) the corresponding time-activity curves of radiotracers for U-87 MG tumors and muscle. Statistical significance was determined using one-way ANOVA followed by Tukey's HSD post hoc test. * p < 0.05.
Fapi 46 Precursor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fapi 46 precursor/product/MedChemExpress
Average 94 stars, based on 1 article reviews
fapi 46 precursor - by Bioz Stars, 2026-03
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fapi 46  (MedChemExpress)
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MedChemExpress fapi 46
Representative chemical structures and functional groups of (A) FAPI-04, (B) <t>FAPI-46,</t> and (C) Alb-FAPtp-01 and (D) the developed peptide tracer (Alb-FAPtp-02). (E) FAP expression level in U-87MG and HEK293T. (F) Cellular uptake of ⁶⁸Ga-FAPI-04, ⁶⁸Ga-FAPI-46, and ⁶⁸Ga-Alb-FAPtp-02 in U-87 MG and HEK293T cells. No significant. (G) Competitive binding assay showing inhibition of tracer uptake in U-87 MG cells by non-radiolabeled FAPI-04, confirming FAP-specific binding (n = 3, mean ± s.d.). ( H ) In vivo dynamic PET imaging analysis comparison of FAP tracers. Representative dynamic PET/CT imaging of ⁶⁸Ga-Alb-FAPtp-02, ⁶⁸Ga-FAPI-46 and ⁶⁸Ga-FAPI-04 in mice with glioma xenografts. (I) the corresponding time-activity curves of radiotracers for U-87 MG tumors and muscle. Statistical significance was determined using one-way ANOVA followed by Tukey's HSD post hoc test. * p < 0.05.
Fapi 46, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fap-ligands fapi-46  (ABX GmbH)
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Representative chemical structures and functional groups of (A) FAPI-04, (B) <t>FAPI-46,</t> and (C) Alb-FAPtp-01 and (D) the developed peptide tracer (Alb-FAPtp-02). (E) FAP expression level in U-87MG and HEK293T. (F) Cellular uptake of ⁶⁸Ga-FAPI-04, ⁶⁸Ga-FAPI-46, and ⁶⁸Ga-Alb-FAPtp-02 in U-87 MG and HEK293T cells. No significant. (G) Competitive binding assay showing inhibition of tracer uptake in U-87 MG cells by non-radiolabeled FAPI-04, confirming FAP-specific binding (n = 3, mean ± s.d.). ( H ) In vivo dynamic PET imaging analysis comparison of FAP tracers. Representative dynamic PET/CT imaging of ⁶⁸Ga-Alb-FAPtp-02, ⁶⁸Ga-FAPI-46 and ⁶⁸Ga-FAPI-04 in mice with glioma xenografts. (I) the corresponding time-activity curves of radiotracers for U-87 MG tumors and muscle. Statistical significance was determined using one-way ANOVA followed by Tukey's HSD post hoc test. * p < 0.05.
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68ga-fapi-46 pet/ct  (Siemens AG)
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Representative chemical structures and functional groups of (A) FAPI-04, (B) <t>FAPI-46,</t> and (C) Alb-FAPtp-01 and (D) the developed peptide tracer (Alb-FAPtp-02). (E) FAP expression level in U-87MG and HEK293T. (F) Cellular uptake of ⁶⁸Ga-FAPI-04, ⁶⁸Ga-FAPI-46, and ⁶⁸Ga-Alb-FAPtp-02 in U-87 MG and HEK293T cells. No significant. (G) Competitive binding assay showing inhibition of tracer uptake in U-87 MG cells by non-radiolabeled FAPI-04, confirming FAP-specific binding (n = 3, mean ± s.d.). ( H ) In vivo dynamic PET imaging analysis comparison of FAP tracers. Representative dynamic PET/CT imaging of ⁶⁸Ga-Alb-FAPtp-02, ⁶⁸Ga-FAPI-46 and ⁶⁸Ga-FAPI-04 in mice with glioma xenografts. (I) the corresponding time-activity curves of radiotracers for U-87 MG tumors and muscle. Statistical significance was determined using one-way ANOVA followed by Tukey's HSD post hoc test. * p < 0.05.
68ga Fapi 46 Pet/Ct, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/68ga-fapi-46 pet/ct/product/Siemens AG
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68ga fapi-46  (Siemens AG)
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Siemens AG 68ga fapi-46
FAPi PET/CT in pulmonary diseases.
68ga Fapi 46, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fapi-46  (CS Bio Inc)
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FAPi PET/CT in pulmonary diseases.
Fapi 46, supplied by CS Bio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Representative chemical structures and functional groups of (A) FAPI-04, (B) FAPI-46, and (C) Alb-FAPtp-01 and (D) the developed peptide tracer (Alb-FAPtp-02). (E) FAP expression level in U-87MG and HEK293T. (F) Cellular uptake of ⁶⁸Ga-FAPI-04, ⁶⁸Ga-FAPI-46, and ⁶⁸Ga-Alb-FAPtp-02 in U-87 MG and HEK293T cells. No significant. (G) Competitive binding assay showing inhibition of tracer uptake in U-87 MG cells by non-radiolabeled FAPI-04, confirming FAP-specific binding (n = 3, mean ± s.d.). ( H ) In vivo dynamic PET imaging analysis comparison of FAP tracers. Representative dynamic PET/CT imaging of ⁶⁸Ga-Alb-FAPtp-02, ⁶⁸Ga-FAPI-46 and ⁶⁸Ga-FAPI-04 in mice with glioma xenografts. (I) the corresponding time-activity curves of radiotracers for U-87 MG tumors and muscle. Statistical significance was determined using one-way ANOVA followed by Tukey's HSD post hoc test. * p < 0.05.

Journal: Theranostics

Article Title: Engineering a modular FAP-targeting ferritin-based drug nanocarrier for enhanced glioblastoma theranostics

doi: 10.7150/thno.125403

Figure Lengend Snippet: Representative chemical structures and functional groups of (A) FAPI-04, (B) FAPI-46, and (C) Alb-FAPtp-01 and (D) the developed peptide tracer (Alb-FAPtp-02). (E) FAP expression level in U-87MG and HEK293T. (F) Cellular uptake of ⁶⁸Ga-FAPI-04, ⁶⁸Ga-FAPI-46, and ⁶⁸Ga-Alb-FAPtp-02 in U-87 MG and HEK293T cells. No significant. (G) Competitive binding assay showing inhibition of tracer uptake in U-87 MG cells by non-radiolabeled FAPI-04, confirming FAP-specific binding (n = 3, mean ± s.d.). ( H ) In vivo dynamic PET imaging analysis comparison of FAP tracers. Representative dynamic PET/CT imaging of ⁶⁸Ga-Alb-FAPtp-02, ⁶⁸Ga-FAPI-46 and ⁶⁸Ga-FAPI-04 in mice with glioma xenografts. (I) the corresponding time-activity curves of radiotracers for U-87 MG tumors and muscle. Statistical significance was determined using one-way ANOVA followed by Tukey's HSD post hoc test. * p < 0.05.

Article Snippet: The FAPI-04 precursor was sourced from KriSan Biotech Co. (Tainan, Taiwan), a PICS/GMP-compliant pharmaceutical manufacturer, whereas the FAPI-46 precursor was purchased from MedChemExpress (MCE, New Jersey, USA).

Techniques: Functional Assay, Expressing, Competitive Binding Assay, Inhibition, Binding Assay, In Vivo, Imaging, Comparison, Positron Emission Tomography-Computed Tomography, Activity Assay

FAPi PET/CT in pulmonary diseases.

Journal: Biomedicines

Article Title: FAPi PET/CT Imaging to Identify Fibrosis in Immune-Mediated Inflammatory Diseases

doi: 10.3390/biomedicines13040775

Figure Lengend Snippet: FAPi PET/CT in pulmonary diseases.

Article Snippet: Rosenkrans et al., 2022 [ ] , 68Ga FAPi-46 and 68Ga-DOTA , Inveon small-animal scanner (Siemens) , 0.8–3.8 MBq for dynamic imaging and 3.8 MBq for static imaging , 0 and 60 min , HU, %IA, %IA/cc, VOI.

Techniques: Control, Comparison, Immunofluorescence, Western Blot, Biomarker Discovery, Staining, Immunohistochemical staining, Expressing, Single Photon Emission Computed Tomography, Activity Assay, Imaging, Immunohistochemistry

FAPi PET/CT in cardiovascular, renal and IgG4-related diseases.

Journal: Biomedicines

Article Title: FAPi PET/CT Imaging to Identify Fibrosis in Immune-Mediated Inflammatory Diseases

doi: 10.3390/biomedicines13040775

Figure Lengend Snippet: FAPi PET/CT in cardiovascular, renal and IgG4-related diseases.

Article Snippet: Rosenkrans et al., 2022 [ ] , 68Ga FAPi-46 and 68Ga-DOTA , Inveon small-animal scanner (Siemens) , 0.8–3.8 MBq for dynamic imaging and 3.8 MBq for static imaging , 0 and 60 min , HU, %IA, %IA/cc, VOI.

Techniques: Control, Comparison, Activity Assay, Fluorescence, Imaging, In Vivo, Clinical Proteomics, Activation Assay, Staining, Immunohistochemical staining

Summary of main characteristics investigated in FAPi PET/CT.

Journal: Biomedicines

Article Title: FAPi PET/CT Imaging to Identify Fibrosis in Immune-Mediated Inflammatory Diseases

doi: 10.3390/biomedicines13040775

Figure Lengend Snippet: Summary of main characteristics investigated in FAPi PET/CT.

Article Snippet: Rosenkrans et al., 2022 [ ] , 68Ga FAPi-46 and 68Ga-DOTA , Inveon small-animal scanner (Siemens) , 0.8–3.8 MBq for dynamic imaging and 3.8 MBq for static imaging , 0 and 60 min , HU, %IA, %IA/cc, VOI.

Techniques: Injection, Imaging, Immunohistochemical staining, Staining, Activity Assay

FAPi PET/CT in gastro-intestinal and hepatic diseases.

Journal: Biomedicines

Article Title: FAPi PET/CT Imaging to Identify Fibrosis in Immune-Mediated Inflammatory Diseases

doi: 10.3390/biomedicines13040775

Figure Lengend Snippet: FAPi PET/CT in gastro-intestinal and hepatic diseases.

Article Snippet: Rosenkrans et al., 2022 [ ] , 68Ga FAPi-46 and 68Ga-DOTA , Inveon small-animal scanner (Siemens) , 0.8–3.8 MBq for dynamic imaging and 3.8 MBq for static imaging , 0 and 60 min , HU, %IA, %IA/cc, VOI.

Techniques: Control, Comparison, Histopathology, Immunohistochemical staining, Staining, Imaging, Diagnostic Assay, Biomarker Discovery, Immunofluorescence, Expressing