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LGC Standards
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Journal: Drug Testing and Analysis
Article Title: High‐throughput liquid chromatography‐vacuum differential mobility spectrometry‐mass spectrometry for the analysis of isomeric drugs of abuse in human urine
doi: 10.1002/dta.3778
Figure Lengend Snippet: Dispersion plots (CV vs. SV) for the isomeric pairs of drugs of abuse (m/z 290) BZE/NCOC, (m/z 250) ODT/NDT, and (m/z 315) THC/CBD. (a) Infusion at 8 μL/min and in (b–f) flow injection analysis at flow rate 50 μL/min with 5% isopropanol, 20% and 80% methanol, and acetonitrile. Data were acquired in SIM mode, and the vDMS was used in scan mode (SV ramp from 0 to 900 V and CV stepped by 0.2 V).
Article Snippet: Cocaine (COC), benzoylecgonine (BZE),
Techniques: Dispersion, Injection
Journal: Drug Testing and Analysis
Article Title: High‐throughput liquid chromatography‐vacuum differential mobility spectrometry‐mass spectrometry for the analysis of isomeric drugs of abuse in human urine
doi: 10.1002/dta.3778
Figure Lengend Snippet: Effect of the increased flow rate, from 8 to 100 μL/min using 20% CH 3 CN (a) and CH 3 CN content, from 20% to 100% at 100 μL/min flow rate (b) for the resolution of isomeric pairs BZE/NCOC and ODT/NDT. vDMS was used in scan mode at SV = 600 V and CV stepped by 0.2 V.
Article Snippet: Cocaine (COC), benzoylecgonine (BZE),
Techniques:
Journal: Drug Testing and Analysis
Article Title: High‐throughput liquid chromatography‐vacuum differential mobility spectrometry‐mass spectrometry for the analysis of isomeric drugs of abuse in human urine
doi: 10.1002/dta.3778
Figure Lengend Snippet: Measured compensation voltage (CV) at SV 600 V by FIA of cocaine and its metabolites including the isomeric metabolites BZE/NCOC (a) and tramadol and its isomeric metabolites ODT/NDT (b) at concentration of 500 ng/mL in SIM mode. Vacuum DMS was used in scan mode (CV stepped by 0.2 V) for optimized separation using 20% CH 3 CN on LC mobile phase at flow rate 100 μL/min.
Article Snippet: Cocaine (COC), benzoylecgonine (BZE),
Techniques: Concentration Assay