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Mean 17β-estradiol and DHEAS concentrations by MDD and menopausal stage, a) Serum estradiol levels in MDD postmenopausal women were significantly lower than non-MDD postmenopausal women and pre/perimenopausal women, regardless of MDD status. As expected, non-MDD postmenopausal women had significantly lower levels of estradiol compared to non-MDD pre/perimenopausal women, b) In non-MDD subjects, men had significantly higher of DHEAS compared to pre/perimenopausal and postmenopausal women. In MDD, men had significantly higher levels of DHEAS compared to postmenopausal women. There were no differences in DHEAS levels between menopausal staging groups in both MDD status. Non-MDD: pre/perimenopause (n = 33), postmenopause (n = 21), men (n = 67); MDD: pre/perimenopause (n = 29), postmenopause (n = 10), men (n = 27). Error bars represent SEM. *p< 0.05.

Journal: Brain research

Article Title: Impact of Adrenal Hormones, Reproductive Aging, and Major Depression on Memory Circuitry Decline in Early Midlife

doi: 10.1016/j.brainres.2019.146303

Figure Lengend Snippet: Mean 17β-estradiol and DHEAS concentrations by MDD and menopausal stage, a) Serum estradiol levels in MDD postmenopausal women were significantly lower than non-MDD postmenopausal women and pre/perimenopausal women, regardless of MDD status. As expected, non-MDD postmenopausal women had significantly lower levels of estradiol compared to non-MDD pre/perimenopausal women, b) In non-MDD subjects, men had significantly higher of DHEAS compared to pre/perimenopausal and postmenopausal women. In MDD, men had significantly higher levels of DHEAS compared to postmenopausal women. There were no differences in DHEAS levels between menopausal staging groups in both MDD status. Non-MDD: pre/perimenopause (n = 33), postmenopause (n = 21), men (n = 67); MDD: pre/perimenopause (n = 29), postmenopause (n = 10), men (n = 27). Error bars represent SEM. *p< 0.05.

Article Snippet: DHEAS concentrations were also determined via CLIA (Beckman Coulter & Abbott).

Techniques:

Phenotype characteristics of the study participants. Statistically significant P ‐values are marked in bold

Journal: Aging Cell

Article Title: Estrogenic regulation of skeletal muscle proteome: a study of premenopausal women and postmenopausal MZ cotwins discordant for hormonal therapy

doi: 10.1111/acel.12661

Figure Lengend Snippet: Phenotype characteristics of the study participants. Statistically significant P ‐values are marked in bold

Article Snippet: Muscular E 2 , testosterone, DHT, and DHEA concentrations were determine using ELISA tests (IBL‐international, Hamburg, Germany) from 1:10 diluted muscle supernatants in duplicates.

Techniques:

The intrapair differences of postmenopausal twins. Statistically significant P ‐values are marked in bold

Journal: Aging Cell

Article Title: Estrogenic regulation of skeletal muscle proteome: a study of premenopausal women and postmenopausal MZ cotwins discordant for hormonal therapy

doi: 10.1111/acel.12661

Figure Lengend Snippet: The intrapair differences of postmenopausal twins. Statistically significant P ‐values are marked in bold

Article Snippet: Muscular E 2 , testosterone, DHT, and DHEA concentrations were determine using ELISA tests (IBL‐international, Hamburg, Germany) from 1:10 diluted muscle supernatants in duplicates.

Techniques: