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germline p/lp variants in the ddx41 gene  (CytoMol Inc)
90
CytoMol Inc germline p/lp variants in the ddx41 gene
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Germline P/Lp Variants In The Ddx41 Gene, supplied by CytoMol Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/germline p/lp variants in the ddx41 gene/product/CytoMol Inc
Average 90 stars, based on 1 article reviews
germline p/lp variants in the ddx41 gene - by Bioz Stars, 2026-04
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ddx41 gene  (CytoMol Inc)
90
CytoMol Inc ddx41 gene
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Ddx41 Gene, supplied by CytoMol Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ddx41 gene/product/CytoMol Inc
Average 90 stars, based on 1 article reviews
ddx41 gene - by Bioz Stars, 2026-04
90/100 stars
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antibodies against ddx41 15076  (Cell Signaling Technology Inc)
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Cell Signaling Technology Inc antibodies against ddx41 15076
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Antibodies Against Ddx41 15076, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/antibodies against ddx41 15076/product/Cell Signaling Technology Inc
Average 90 stars, based on 1 article reviews
antibodies against ddx41 15076 - by Bioz Stars, 2026-04
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anti ddx41  (Proteintech)
93
Proteintech anti ddx41
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Anti Ddx41, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti ddx41/product/Proteintech
Average 93 stars, based on 1 article reviews
anti ddx41 - by Bioz Stars, 2026-04
93/100 stars
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antibodies anti-ddx41  (Novus Biologicals)
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Novus Biologicals antibodies anti-ddx41
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Antibodies Anti Ddx41, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/antibodies anti-ddx41/product/Novus Biologicals
Average 90 stars, based on 1 article reviews
antibodies anti-ddx41 - by Bioz Stars, 2026-04
90/100 stars
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ddx41 genetic  (CytoMol Inc)
90
CytoMol Inc ddx41 genetic
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Ddx41 Genetic, supplied by CytoMol Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ddx41 genetic/product/CytoMol Inc
Average 90 stars, based on 1 article reviews
ddx41 genetic - by Bioz Stars, 2026-04
90/100 stars
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germline ddx41 p/lp variants  (CytoMol Inc)
90
CytoMol Inc germline ddx41 p/lp variants
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Germline Ddx41 P/Lp Variants, supplied by CytoMol Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/germline ddx41 p/lp variants/product/CytoMol Inc
Average 90 stars, based on 1 article reviews
germline ddx41 p/lp variants - by Bioz Stars, 2026-04
90/100 stars
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ddx41  (Cell Signaling Technology Inc)
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Cell Signaling Technology Inc ddx41
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Ddx41, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ddx41/product/Cell Signaling Technology Inc
Average 93 stars, based on 1 article reviews
ddx41 - by Bioz Stars, 2026-04
93/100 stars
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Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Journal: Clinical Cancer Research

Article Title: Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study

doi: 10.1158/1078-0432.CCR-24-4251

Figure Lengend Snippet: Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Article Snippet: Overall, germline P/LP variants in the DDX41 gene were the most common finding, although predominantly in the CytoMol group, in line with previous studies ( , ).

Techniques: Diagnostic Assay, Comparison

Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Journal: Clinical Cancer Research

Article Title: Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study

doi: 10.1158/1078-0432.CCR-24-4251

Figure Lengend Snippet: Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Article Snippet: The most frequently mutated gene was DDX41 , which accounted for 43% (13/30) of P/LP findings across all criteria and for 70% (12/17) of findings in the CytoMol group ( ).

Techniques: Diagnostic Assay, Comparison