Review





Similar Products

gene exp ddx41 hs00169602 m1  (Thermo Fisher)
85
Thermo Fisher gene exp ddx41 hs00169602 m1
Gene Exp Ddx41 Hs00169602 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ddx41+gene/Gene+Exp%2E+DDX41%2C+Hs00169602_m1/pm39453476-59-28-29
Average 85 stars, based on 1 article reviews
gene exp ddx41 hs00169602 m1 - by Bioz Stars, 2026-09
85/100 stars
  Buy from Supplier
germline p/lp variants in the ddx41 gene  (CytoMol Inc)
90
CytoMol Inc germline p/lp variants in the ddx41 gene
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Germline P/Lp Variants In The Ddx41 Gene, supplied by CytoMol Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ddx41+gene/germline+p+lp+variants+in+the+ddx41+gene/pmc12260513-151-6-17
Average 90 stars, based on 1 article reviews
germline p/lp variants in the ddx41 gene - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
ddx41 gene  (CytoMol Inc)
90
CytoMol Inc ddx41 gene
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Ddx41 Gene, supplied by CytoMol Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ddx41+gene/germline+p+lp+variants+in+the+ddx41+gene/pmc12260513-93-6-27
Average 90 stars, based on 1 article reviews
ddx41 gene - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
open reading frame of the ddx41 gene  (Thermo Fisher)
90
Thermo Fisher open reading frame of the ddx41 gene
Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in <t>DDX41</t> genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.
Open Reading Frame Of The Ddx41 Gene, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ddx41+gene/sh+constructs+targeting+ddx41/pm28426938-23-29-22
Average 90 stars, based on 1 article reviews
open reading frame of the ddx41 gene - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Journal: Clinical Cancer Research

Article Title: Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study

doi: 10.1158/1078-0432.CCR-24-4251

Figure Lengend Snippet: Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Article Snippet: Overall, germline P/LP variants in the DDX41 gene were the most common finding, although predominantly in the CytoMol group, in line with previous studies ( , ).

Techniques: Diagnostic Assay, Comparison

Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Journal: Clinical Cancer Research

Article Title: Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study

doi: 10.1158/1078-0432.CCR-24-4251

Figure Lengend Snippet: Clinical characteristics and selected pedigrees. A, Boxplot of age at inclusion for the three diagnostic outcomes with regard to findings in established genes for hereditary blood disorders. “None” refers to patients without any findings. Actual data points are overlaid, their shape illustrating the hematologic phenotype at inclusion. Patients with germline findings in DDX41 genes are presented in red. A Wilcoxon rank-sum test was performed for pairwise comparison of age at inclusion. Adjusted P values are indicated above the boxplot. Ns, not significant. B, Pedigree of three patients belonging to families with inherited thrombocytopenia without hematologic malignancies harboring germline pathogenic variants in ANKRD26 ( NM_014915.2 ). Affected individuals are represented by filled squares (males) and circles (females). The index case is denoted by an arrow. Number or “n” within the symbols represents the known or unknown number of relatives, respectively. P, Pathogenic; TP, thrombocytopenia.

Article Snippet: The most frequently mutated gene was DDX41 , which accounted for 43% (13/30) of P/LP findings across all criteria and for 70% (12/17) of findings in the CytoMol group ( ).

Techniques: Diagnostic Assay, Comparison