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Effects of social-SPS and MSG on the levels of GHS-R1 a , Ob-R b , D2R c , and D1R d in the hypothalamus of male rats. Results represent the mean ± S.E.M. of 5 rats per group. * p < .05; ** p < .01; *** p < .001; **** p < .0001 when compared with saline control group. Data were analyzed by two-way ANOVA followed by the Sidak’s post-test. MSG means monosodium glutamate, social-SPS means social-single prolonged stress, GHS-R1 means Ghrelin receptor 1, Ob-R means leptin receptor, D2R means dopamine receptor 2, D1R means dopamine receptor 1

Journal: Metabolic Brain Disease

Article Title: Sex-dependent behavioral and hypothalamic receptor changes after early-life monosodium glutamate (MSG) exposure and adult social stress in Wistar rats

doi: 10.1007/s11011-026-01825-9

Figure Lengend Snippet: Effects of social-SPS and MSG on the levels of GHS-R1 a , Ob-R b , D2R c , and D1R d in the hypothalamus of male rats. Results represent the mean ± S.E.M. of 5 rats per group. * p < .05; ** p < .01; *** p < .001; **** p < .0001 when compared with saline control group. Data were analyzed by two-way ANOVA followed by the Sidak’s post-test. MSG means monosodium glutamate, social-SPS means social-single prolonged stress, GHS-R1 means Ghrelin receptor 1, Ob-R means leptin receptor, D2R means dopamine receptor 2, D1R means dopamine receptor 1

Article Snippet: The proteins: Ob-R anti-mouse, Santa Cruz, 1:1000; GHS-R1 anti-mouse, Santa Cruz, 1:1000; D1R anti-mouse, Santa Cruz, 1:250; and D2R anti-mouse, Santa Cruz, 1:250; were marked.

Techniques: Saline, Control

Effects of social-SPS and MSG on the levels of GHS-R1 a, Ob-R b, D2R c, and D1R d in thehypothalamus of female rats. Results represent the mean ± S.E.M. of 5 rats per group. *p < .05; **p < .01;when compared with saline control group. Data were analyzed by two-way ANOVA followed by theSidak’s post-test. MSG means monosodium glutamate, social-SPS means social-single prolonged stress,GHS-R1 means Ghrelin receptor 1, Ob-R means leptin receptor, D2R means dopamine receptor 2, D1Rmeans dopamine receptor 1

Journal: Metabolic Brain Disease

Article Title: Sex-dependent behavioral and hypothalamic receptor changes after early-life monosodium glutamate (MSG) exposure and adult social stress in Wistar rats

doi: 10.1007/s11011-026-01825-9

Figure Lengend Snippet: Effects of social-SPS and MSG on the levels of GHS-R1 a, Ob-R b, D2R c, and D1R d in thehypothalamus of female rats. Results represent the mean ± S.E.M. of 5 rats per group. *p < .05; **p < .01;when compared with saline control group. Data were analyzed by two-way ANOVA followed by theSidak’s post-test. MSG means monosodium glutamate, social-SPS means social-single prolonged stress,GHS-R1 means Ghrelin receptor 1, Ob-R means leptin receptor, D2R means dopamine receptor 2, D1Rmeans dopamine receptor 1

Article Snippet: The proteins: Ob-R anti-mouse, Santa Cruz, 1:1000; GHS-R1 anti-mouse, Santa Cruz, 1:1000; D1R anti-mouse, Santa Cruz, 1:250; and D2R anti-mouse, Santa Cruz, 1:250; were marked.

Techniques: Saline, Control

Pearson’s correlation test between hypothalamic levels of D2R and food intake a , D2R and GHS-R1 b , D2R and Ob-R c , and between anxiety index and food intake d in male rats. In female rats, correlation between anxiety index and food intake e , D1R levels and anxiety levels f , and D1R and food intake g . Each point represents one individual animal. GHS-R1 means Ghrelin receptor 1, Ob-R means leptin receptor, D2R means dopamine receptor 2, D1R means dopamine receptor 1

Journal: Metabolic Brain Disease

Article Title: Sex-dependent behavioral and hypothalamic receptor changes after early-life monosodium glutamate (MSG) exposure and adult social stress in Wistar rats

doi: 10.1007/s11011-026-01825-9

Figure Lengend Snippet: Pearson’s correlation test between hypothalamic levels of D2R and food intake a , D2R and GHS-R1 b , D2R and Ob-R c , and between anxiety index and food intake d in male rats. In female rats, correlation between anxiety index and food intake e , D1R levels and anxiety levels f , and D1R and food intake g . Each point represents one individual animal. GHS-R1 means Ghrelin receptor 1, Ob-R means leptin receptor, D2R means dopamine receptor 2, D1R means dopamine receptor 1

Article Snippet: The proteins: Ob-R anti-mouse, Santa Cruz, 1:1000; GHS-R1 anti-mouse, Santa Cruz, 1:1000; D1R anti-mouse, Santa Cruz, 1:250; and D2R anti-mouse, Santa Cruz, 1:250; were marked.

Techniques: