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TSP-1 promotes the translocation of CRT to the cell surface in MC-3 cells. Cells were stained with an <t>APC-conjugated</t> <t>anti-CRT</t> antibody, and CRT expression on the cell membrane is presented as mean fluorescence intensity. At the 72 h point: **P<0.01 vs. the control group; # P<0.05 vs. the TSP-1 group; and ▲ P<0.05 vs. the TSP-1 + ISRIB group. MFI, mean fluorescence intensity; CRT, calreticulin; TSP-1, thrombospondin-1.
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replanning ct ct1  (Varian Medical)
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TSP-1 promotes the translocation of CRT to the cell surface in MC-3 cells. Cells were stained with an <t>APC-conjugated</t> <t>anti-CRT</t> antibody, and CRT expression on the cell membrane is presented as mean fluorescence intensity. At the 72 h point: **P<0.01 vs. the control group; # P<0.05 vs. the TSP-1 group; and ▲ P<0.05 vs. the TSP-1 + ISRIB group. MFI, mean fluorescence intensity; CRT, calreticulin; TSP-1, thrombospondin-1.
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madit crt  (Boston Scientific Corporation)
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Estimated ICERs and 95% CIs for <t>the</t> <t>MADIT-CRT</t> and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).
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Estimated ICERs and 95% CIs for <t>the</t> <t>MADIT-CRT</t> and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).
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Estimated ICERs and 95% CIs for <t>the</t> <t>MADIT-CRT</t> and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).
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crt d implantation  (Biostar Inc)
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Estimated ICERs and 95% CIs for <t>the</t> <t>MADIT-CRT</t> and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).
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Estimated ICERs and 95% CIs for <t>the</t> <t>MADIT-CRT</t> and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).
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Estimated ICERs and 95% CIs for <t>the</t> <t>MADIT-CRT</t> and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).
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Estimated ICERs and 95% CIs for <t>the</t> <t>MADIT-CRT</t> and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).
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Image Search Results


TSP-1 promotes the translocation of CRT to the cell surface in MC-3 cells. Cells were stained with an APC-conjugated anti-CRT antibody, and CRT expression on the cell membrane is presented as mean fluorescence intensity. At the 72 h point: **P<0.01 vs. the control group; # P<0.05 vs. the TSP-1 group; and ▲ P<0.05 vs. the TSP-1 + ISRIB group. MFI, mean fluorescence intensity; CRT, calreticulin; TSP-1, thrombospondin-1.

Journal: Oncology Letters

Article Title: Thrombospondin-1 triggers calreticulin expression in human mucoepidermoid carcinoma MC-3 cells via the PERK/CHOP pathway

doi: 10.3892/ol.2026.15589

Figure Lengend Snippet: TSP-1 promotes the translocation of CRT to the cell surface in MC-3 cells. Cells were stained with an APC-conjugated anti-CRT antibody, and CRT expression on the cell membrane is presented as mean fluorescence intensity. At the 72 h point: **P<0.01 vs. the control group; # P<0.05 vs. the TSP-1 group; and ▲ P<0.05 vs. the TSP-1 + ISRIB group. MFI, mean fluorescence intensity; CRT, calreticulin; TSP-1, thrombospondin-1.

Article Snippet: Primary antibodies, including anti-PERK (1:1,000; cat. no. MA8131; Abmart Pharmaceutical Technology Co., Ltd.), anti-CHOP (1:1,000; cat. no. WL00880; Wanleibio Co., Ltd.), anti-CRT (1:800; cat. no. bs-5913R; BIOSS) and anti-β-actin (1:5,000; cat. no. 66009-1-Ig; Proteintech Group Inc.), were diluted in 5% BSA and incubated with the membranes overnight at 4°C.

Techniques: Translocation Assay, Staining, Expressing, Membrane, Fluorescence, Control

TSP-1 effects on cell surface CRT expression at 4 h. Cells were stained with an APC-conjugated anti-CRT antibody, and CRT expression on the cell membrane is presented as mean fluorescence intensity. At the 4 h time point. *P<0.05 compared with control group; # P<0.05 compared with TSP-1 action group; and ▲ P<0.05 compared with TSP-1 + ISRIB group. TSP-1, thrombospondin-1; CRT, calreticulin.

Journal: Oncology Letters

Article Title: Thrombospondin-1 triggers calreticulin expression in human mucoepidermoid carcinoma MC-3 cells via the PERK/CHOP pathway

doi: 10.3892/ol.2026.15589

Figure Lengend Snippet: TSP-1 effects on cell surface CRT expression at 4 h. Cells were stained with an APC-conjugated anti-CRT antibody, and CRT expression on the cell membrane is presented as mean fluorescence intensity. At the 4 h time point. *P<0.05 compared with control group; # P<0.05 compared with TSP-1 action group; and ▲ P<0.05 compared with TSP-1 + ISRIB group. TSP-1, thrombospondin-1; CRT, calreticulin.

Article Snippet: Primary antibodies, including anti-PERK (1:1,000; cat. no. MA8131; Abmart Pharmaceutical Technology Co., Ltd.), anti-CHOP (1:1,000; cat. no. WL00880; Wanleibio Co., Ltd.), anti-CRT (1:800; cat. no. bs-5913R; BIOSS) and anti-β-actin (1:5,000; cat. no. 66009-1-Ig; Proteintech Group Inc.), were diluted in 5% BSA and incubated with the membranes overnight at 4°C.

Techniques: Expressing, Staining, Membrane, Fluorescence, Control

Estimated ICERs and 95% CIs for the MADIT-CRT and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).

Journal: Biometrics

Article Title: Regression methods for cost-effectiveness analysis with different censoring times or terminating events for survival time and costs

doi: 10.1093/biomtc/ujag073

Figure Lengend Snippet: Estimated ICERs and 95% CIs for the MADIT-CRT and MADIT-II trials. The dots represent 1000 bootstrap samples. The solid lines denote the estimated ICERs; the black dashed lines and the gray dot-dashed lines indicate CI limits obtained by the IMP method and the bootstrap method, respectively. Panels (A) and (B) present results using HF-free QAL as the effectiveness measure for the LBBB and non-LBBB subgroups in the MADIT-CRT study (4-year time horizon). Panel (C) presents results using YOL as the effectiveness measure in the MADIT-II study (3.5-year time horizon).

Article Snippet: While the data transfer and use agreements prohibit making the MADIT-CRT and MADIT-II datasets publicly available, Boston Scientific may share the data with qualified researchers, available at https://www.bostonscientific.com/en-US/data-sharing-requests.html

Techniques: