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Image Search Results


Overall representation for the preparation of 5-ALA-CQD-Glu-β-CD nanocarrier.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: Overall representation for the preparation of 5-ALA-CQD-Glu-β-CD nanocarrier.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques:

FTIR spectra of (a) Ts-β-CD, (b) BOC-Glu, (c) Ts-β-CD- g -BOC-Glu, (d) CQD, (e) CQD-Glu-β-CD, (f) 5-ALA-CQD-Glu-β-CD, and (g) DOX/5-ALA-CQD-Glu-β-CD nanocarrier.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: FTIR spectra of (a) Ts-β-CD, (b) BOC-Glu, (c) Ts-β-CD- g -BOC-Glu, (d) CQD, (e) CQD-Glu-β-CD, (f) 5-ALA-CQD-Glu-β-CD, and (g) DOX/5-ALA-CQD-Glu-β-CD nanocarrier.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques:

XRD pattern of (a) Ts-β-CD, (b) BOC-Glu, (c) Ts-β-CD- g -BOC-Glu, (d) CQD (e) CQD-Glu-β-CD, (f) 5-ALA-CQD-Glu-β-CD, and (f) DOX/5-ALA-CQD-Glu-β-CD nanocarrier.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: XRD pattern of (a) Ts-β-CD, (b) BOC-Glu, (c) Ts-β-CD- g -BOC-Glu, (d) CQD (e) CQD-Glu-β-CD, (f) 5-ALA-CQD-Glu-β-CD, and (f) DOX/5-ALA-CQD-Glu-β-CD nanocarrier.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques:

TEM images with SEAD spectrum of (a) CQD, (b) 5-ALA-CQD-BOC-Glu-β-CD, and (c) DOX/5-ALA-CQD-BOC-Glu-β-CD nanocarrier.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: TEM images with SEAD spectrum of (a) CQD, (b) 5-ALA-CQD-BOC-Glu-β-CD, and (c) DOX/5-ALA-CQD-BOC-Glu-β-CD nanocarrier.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques:

The AFM images of 2D, 3D, and topographical images of (a–c) CQD, (d–f) 5-ALA-CQD-BOC-Glu-β-CD, and (g–i) DOX/5-ALA-CQD-BOC-Glu-β-CD nanocarrier.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: The AFM images of 2D, 3D, and topographical images of (a–c) CQD, (d–f) 5-ALA-CQD-BOC-Glu-β-CD, and (g–i) DOX/5-ALA-CQD-BOC-Glu-β-CD nanocarrier.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques:

UV–vis spectrum (a) encapsulation efficiency and (b) loading capacity of DOX/5-ALA-CQD-BOC-Glu-β-CD nanocarrier.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: UV–vis spectrum (a) encapsulation efficiency and (b) loading capacity of DOX/5-ALA-CQD-BOC-Glu-β-CD nanocarrier.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques:

In vitro drug release behavior of 5-ALA and DOX drug from DOX/5-ALA-CQD-BOC-Glu-β-CD under three different physiological pHs (A) 2.8, (B) 5.5, (C) 6.8 at 27 °C for 24 h (A–C). Cumulative drug release (%) behavior (D–F).

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: In vitro drug release behavior of 5-ALA and DOX drug from DOX/5-ALA-CQD-BOC-Glu-β-CD under three different physiological pHs (A) 2.8, (B) 5.5, (C) 6.8 at 27 °C for 24 h (A–C). Cumulative drug release (%) behavior (D–F).

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques: In Vitro

In vitro morphological changes of fibroblast (WS-1) cell line treated with 5-ALA CQD-Glu-β-CD and DOX/5-ALA-CQD-Glu-β-CD nanocarrier in a various time-dependent manner such as 6 h, 12 h, 18 h, and 24 h and IC 50 concentration of 60 μg/mL at scale bar: ∼50 μm.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: In vitro morphological changes of fibroblast (WS-1) cell line treated with 5-ALA CQD-Glu-β-CD and DOX/5-ALA-CQD-Glu-β-CD nanocarrier in a various time-dependent manner such as 6 h, 12 h, 18 h, and 24 h and IC 50 concentration of 60 μg/mL at scale bar: ∼50 μm.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques: In Vitro, Concentration Assay

In vitro morphological changes by the chemo-photodynamic effect of breast cancer (MCF-7) cell treated with DOX/CQD-Glu-β-CD, 5-ALA-CQD-Glu-β-CD, and DOX/5-ALA-CQD-Glu-β-CD nanocarrier with and without irradiation in various time-dependent manners such as 6 h, 12 h, 18 h, and 24 h and IC 50 concentration of 60 μg/mL at scale bar: ∼100 μm.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: In vitro morphological changes by the chemo-photodynamic effect of breast cancer (MCF-7) cell treated with DOX/CQD-Glu-β-CD, 5-ALA-CQD-Glu-β-CD, and DOX/5-ALA-CQD-Glu-β-CD nanocarrier with and without irradiation in various time-dependent manners such as 6 h, 12 h, 18 h, and 24 h and IC 50 concentration of 60 μg/mL at scale bar: ∼100 μm.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques: In Vitro, Irradiation, Concentration Assay

Fluorescent microscopic images of breast cancer (MCF-7) cell line incubated with DOX-loaded CQD-Glu-β-CD, and DOX-loaded 5-ALA-CQD-Glu-β-CD nanocarrier without and with laser irradiation in a various time-dependent manner such as 6 h, 12 h, 18 h, and 24 h and IC 50 concentration of 60 μg/mL respectively at scale bar: ∼30 μm.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: Fluorescent microscopic images of breast cancer (MCF-7) cell line incubated with DOX-loaded CQD-Glu-β-CD, and DOX-loaded 5-ALA-CQD-Glu-β-CD nanocarrier without and with laser irradiation in a various time-dependent manner such as 6 h, 12 h, 18 h, and 24 h and IC 50 concentration of 60 μg/mL respectively at scale bar: ∼30 μm.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques: Incubation, Irradiation, Concentration Assay

ROS level evaluation under irradiation in 6 h incubation with DOX/5-ALA-CQD-Glu-β-CD nanocarrier in breast cancer (MCF-7) cell line without (a–c) and with radiation (d–f) scale bar: ∼10 μm.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: ROS level evaluation under irradiation in 6 h incubation with DOX/5-ALA-CQD-Glu-β-CD nanocarrier in breast cancer (MCF-7) cell line without (a–c) and with radiation (d–f) scale bar: ∼10 μm.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques: Irradiation, Incubation

Qualitative assessment of fluorescence intensity associated with MCF-7 cells by the incubation of coumarin-6 loaded CQD-Glu-β-CD nanocarrier for 1 (a), 3 (b), 6 (c), and 12 h using blue filter (excitation wavelength 460–490 nm, emission 470 nm) in inverted fluorescence microscopy.

Journal: Drug Delivery

Article Title: Combined photodynamic-chemotherapy investigation of cancer cells using carbon quantum dot-based drug carrier system

doi: 10.1080/10717544.2020.1765431

Figure Lengend Snippet: Qualitative assessment of fluorescence intensity associated with MCF-7 cells by the incubation of coumarin-6 loaded CQD-Glu-β-CD nanocarrier for 1 (a), 3 (b), 6 (c), and 12 h using blue filter (excitation wavelength 460–490 nm, emission 470 nm) in inverted fluorescence microscopy.

Article Snippet: 5-ALA was tagged with CQD functionalized mono-(5-BOC-protected-glutamine-6-deoxy) β-cyclodextrin via EDC/NHS chemistry.

Techniques: Fluorescence, Incubation, Microscopy