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Evaluation of 1a – n against Molt4/C8, CEM and L1210 cells and the interplanar angles θ A and θ B .

Journal: Medicines

Article Title: Does Ortho-Substitution Enhance Cytotoxic Potencies in a Series of 3,5-Bis(benzylidene)-4-piperidones?

doi: 10.3390/medicines11080019

Figure Lengend Snippet: Evaluation of 1a – n against Molt4/C8, CEM and L1210 cells and the interplanar angles θ A and θ B .

Article Snippet: The evaluations of cytotoxicity of 1a – n against the human leukemia T-lymphoblast cell line Molt4/C8 (accession number: CVCL_F827; database name: Cellosaurus), human T-cell lymphoma CEM (CVCL_0207) and mouse lymphocytic leukemic cells L1210 (CVCL_0382) (purchased from ATCC) in suspension culture were undertaken at 37 °C with the neoplasms for 48 h (L1210 cells) or 72 h (Molt4/C8 and CEM) in RPMI1640 medium supplemented with fetal bovine serum (FBS) [ ].

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