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The specific information of DEGs

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: The specific information of DEGs

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing, Binding Assay

The relationship between MDG expression and the prognosis of HCC patients. (a–c) Kaplan-Meier estimated survival curves of CDC42, EIF2AK1 and MMP9 were constructed using TCGA clinical data. (d–f) Kaplan-Meier estimated survival curves of CDC42, EIF2AK1 and MMP9 were constructed using ICGC clinical data

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: The relationship between MDG expression and the prognosis of HCC patients. (a–c) Kaplan-Meier estimated survival curves of CDC42, EIF2AK1 and MMP9 were constructed using TCGA clinical data. (d–f) Kaplan-Meier estimated survival curves of CDC42, EIF2AK1 and MMP9 were constructed using ICGC clinical data

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing, Construct

ROC analysis of the CDC42, EIF2AK1 and MMP9 signatures in HCC. (a) ROC analysis of the TCGA database. (b) ROC analysis of the ICGC database

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: ROC analysis of the CDC42, EIF2AK1 and MMP9 signatures in HCC. (a) ROC analysis of the TCGA database. (b) ROC analysis of the ICGC database

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques:

Univariate and Multivariate analyses of factors associated with survival of patients with HCC in TCGA database and ICGC database

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: Univariate and Multivariate analyses of factors associated with survival of patients with HCC in TCGA database and ICGC database

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing

CDC42 expression is upregulated in primary HCC. (a) CDC42 expression in the Roessler liver dataset in Oncomine. (b) CDC42 expression in the Mas liver dataset in Oncomine. (c) CDC42 expression in the Wurmbach liver dataset in Oncomine

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: CDC42 expression is upregulated in primary HCC. (a) CDC42 expression in the Roessler liver dataset in Oncomine. (b) CDC42 expression in the Mas liver dataset in Oncomine. (c) CDC42 expression in the Wurmbach liver dataset in Oncomine

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing

Immunohistochemistry confirmed the differential expression of CDC42. (a) The expression of CDC42 in normal tissue. (b) The expression of CDC42 in tumor tissue

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: Immunohistochemistry confirmed the differential expression of CDC42. (a) The expression of CDC42 in normal tissue. (b) The expression of CDC42 in tumor tissue

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Immunohistochemistry, Quantitative Proteomics, Expressing

The immune infiltration levels of six immune cell types associated with CDC42 expression were analyzed based on the TIMER database. (a–f) CDC42 expression positively correlates with the infiltration of B cells (a), CD4 + T cells (b), CD8 + T cells (c), dendritic cells (d), macrophages (e), and neutrophils (f)

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: The immune infiltration levels of six immune cell types associated with CDC42 expression were analyzed based on the TIMER database. (a–f) CDC42 expression positively correlates with the infiltration of B cells (a), CD4 + T cells (b), CD8 + T cells (c), dendritic cells (d), macrophages (e), and neutrophils (f)

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing

Correlation analyses between CDC42 expression and M2 macrophage markers. (a–d) The expression of CDC42 was significantly correlated with M2 macrophage markers (CD163, MMP2, MMP9, and STAT3) in the TCGA database. (e–h) The expression of CDC42 was significantly correlated with M2 macrophage markers (CD163, MMP2, MMP9, and STAT3) in the ICGC database

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: Correlation analyses between CDC42 expression and M2 macrophage markers. (a–d) The expression of CDC42 was significantly correlated with M2 macrophage markers (CD163, MMP2, MMP9, and STAT3) in the TCGA database. (e–h) The expression of CDC42 was significantly correlated with M2 macrophage markers (CD163, MMP2, MMP9, and STAT3) in the ICGC database

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing

Correlation analyses between CDC42 expression and immune checkpoint inhibitors

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: Correlation analyses between CDC42 expression and immune checkpoint inhibitors

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing

Enrichment plots from GSEA. (a) CDC42 expression positively correlated with the Wnt signaling pathway in the TCGA dataset. (b) CDC42 expression positively correlated with the Wnt signaling pathway in the ICGC dataset

Journal: Bioengineered

Article Title: Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

doi: 10.1080/21655979.2020.1868119

Figure Lengend Snippet: Enrichment plots from GSEA. (a) CDC42 expression positively correlated with the Wnt signaling pathway in the TCGA dataset. (b) CDC42 expression positively correlated with the Wnt signaling pathway in the ICGC dataset

Article Snippet: The CDC42 protein expression level and distribution in HCC tissues and liver tissues were analyzed using the Human Protein Atlas (HPA) database ( https://www.proteinatlas.org/ ).

Techniques: Expressing