Review





Similar Products

temsirolimus cci 779  (MedChemExpress)
94
MedChemExpress temsirolimus cci 779
The PI3K/Akt/mTOR pathway is essential for HAdV-11 replication in ESCC cell lines. ( A ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, the mRNA expression levels were determined using quantitative polymerase chain reaction (qPCR). ( B , D , E , F , H and I ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, and Western blot analysis of mTOR, p-DRP1, PARK2, LC3 and GPX4 expression. ( C ) Cells were pretreated with Temsirolimus <t>(CCI-779)</t> (10 nM) for 2 h, and then infected with HAdV-11 at an MOI of 2 for 48 h. The mitochondrial mass was estimated by MTG staining. ( H ) After pretreatment with 0.5 µM mTOR agonist (MHY1485) for 2 h, cells were infected with HAdV-11 at a MOI of 2 for 48 h. Subsequently, the cells were stained with either C11-BODIPY or Fe 2+ and quantified using flow cytometry. ( J ) Cells were pretreated with CCI-779 for 2 h, and then infected with HAdV-11 at an MOI of 2 for 72 h. Infectious virus production was assessed by titration on JH293 cells and the titer as PFU/cell calculated. The half maximal effective concentration (EC50) for each sample was calculated. Data are cumulative results from 3 experiments ( A , J ) or are representative of 3 independent experiments ( B , C , D , E , F , G , H , I ). Data are presented as mean ± SD ( A , C , E , F , G , H , I , J ). Differences analyzed using a one-way ANOVA with Bonferroni’s post hoc correction ( C , E , F , G , H , I ) or two-tailed t-test ( A , J ) ( n = 3)
Temsirolimus Cci 779, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/temsirolimus cci 779/product/MedChemExpress
Average 94 stars, based on 1 article reviews
temsirolimus cci 779 - by Bioz Stars, 2026-05
94/100 stars
  Buy from Supplier
talysurf cci lite optical profilometer  (Taylor Hobson)
86
Taylor Hobson talysurf cci lite optical profilometer
The PI3K/Akt/mTOR pathway is essential for HAdV-11 replication in ESCC cell lines. ( A ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, the mRNA expression levels were determined using quantitative polymerase chain reaction (qPCR). ( B , D , E , F , H and I ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, and Western blot analysis of mTOR, p-DRP1, PARK2, LC3 and GPX4 expression. ( C ) Cells were pretreated with Temsirolimus <t>(CCI-779)</t> (10 nM) for 2 h, and then infected with HAdV-11 at an MOI of 2 for 48 h. The mitochondrial mass was estimated by MTG staining. ( H ) After pretreatment with 0.5 µM mTOR agonist (MHY1485) for 2 h, cells were infected with HAdV-11 at a MOI of 2 for 48 h. Subsequently, the cells were stained with either C11-BODIPY or Fe 2+ and quantified using flow cytometry. ( J ) Cells were pretreated with CCI-779 for 2 h, and then infected with HAdV-11 at an MOI of 2 for 72 h. Infectious virus production was assessed by titration on JH293 cells and the titer as PFU/cell calculated. The half maximal effective concentration (EC50) for each sample was calculated. Data are cumulative results from 3 experiments ( A , J ) or are representative of 3 independent experiments ( B , C , D , E , F , G , H , I ). Data are presented as mean ± SD ( A , C , E , F , G , H , I , J ). Differences analyzed using a one-way ANOVA with Bonferroni’s post hoc correction ( C , E , F , G , H , I ) or two-tailed t-test ( A , J ) ( n = 3)
Talysurf Cci Lite Optical Profilometer, supplied by Taylor Hobson, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/talysurf cci lite optical profilometer/product/Taylor Hobson
Average 86 stars, based on 1 article reviews
talysurf cci lite optical profilometer - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier
ccis ef-n plan achromat 10× lens  (Motic Group)
86
Motic Group ccis ef-n plan achromat 10× lens
The PI3K/Akt/mTOR pathway is essential for HAdV-11 replication in ESCC cell lines. ( A ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, the mRNA expression levels were determined using quantitative polymerase chain reaction (qPCR). ( B , D , E , F , H and I ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, and Western blot analysis of mTOR, p-DRP1, PARK2, LC3 and GPX4 expression. ( C ) Cells were pretreated with Temsirolimus <t>(CCI-779)</t> (10 nM) for 2 h, and then infected with HAdV-11 at an MOI of 2 for 48 h. The mitochondrial mass was estimated by MTG staining. ( H ) After pretreatment with 0.5 µM mTOR agonist (MHY1485) for 2 h, cells were infected with HAdV-11 at a MOI of 2 for 48 h. Subsequently, the cells were stained with either C11-BODIPY or Fe 2+ and quantified using flow cytometry. ( J ) Cells were pretreated with CCI-779 for 2 h, and then infected with HAdV-11 at an MOI of 2 for 72 h. Infectious virus production was assessed by titration on JH293 cells and the titer as PFU/cell calculated. The half maximal effective concentration (EC50) for each sample was calculated. Data are cumulative results from 3 experiments ( A , J ) or are representative of 3 independent experiments ( B , C , D , E , F , G , H , I ). Data are presented as mean ± SD ( A , C , E , F , G , H , I , J ). Differences analyzed using a one-way ANOVA with Bonferroni’s post hoc correction ( C , E , F , G , H , I ) or two-tailed t-test ( A , J ) ( n = 3)
Ccis Ef N Plan Achromat 10× Lens, supplied by Motic Group, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ccis ef-n plan achromat 10× lens/product/Motic Group
Average 86 stars, based on 1 article reviews
ccis ef-n plan achromat 10× lens - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier
cci surgery  (Charles River Laboratories)
86
Charles River Laboratories cci surgery
The PI3K/Akt/mTOR pathway is essential for HAdV-11 replication in ESCC cell lines. ( A ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, the mRNA expression levels were determined using quantitative polymerase chain reaction (qPCR). ( B , D , E , F , H and I ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, and Western blot analysis of mTOR, p-DRP1, PARK2, LC3 and GPX4 expression. ( C ) Cells were pretreated with Temsirolimus <t>(CCI-779)</t> (10 nM) for 2 h, and then infected with HAdV-11 at an MOI of 2 for 48 h. The mitochondrial mass was estimated by MTG staining. ( H ) After pretreatment with 0.5 µM mTOR agonist (MHY1485) for 2 h, cells were infected with HAdV-11 at a MOI of 2 for 48 h. Subsequently, the cells were stained with either C11-BODIPY or Fe 2+ and quantified using flow cytometry. ( J ) Cells were pretreated with CCI-779 for 2 h, and then infected with HAdV-11 at an MOI of 2 for 72 h. Infectious virus production was assessed by titration on JH293 cells and the titer as PFU/cell calculated. The half maximal effective concentration (EC50) for each sample was calculated. Data are cumulative results from 3 experiments ( A , J ) or are representative of 3 independent experiments ( B , C , D , E , F , G , H , I ). Data are presented as mean ± SD ( A , C , E , F , G , H , I , J ). Differences analyzed using a one-way ANOVA with Bonferroni’s post hoc correction ( C , E , F , G , H , I ) or two-tailed t-test ( A , J ) ( n = 3)
Cci Surgery, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cci surgery/product/Charles River Laboratories
Average 86 stars, based on 1 article reviews
cci surgery - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier
cci group  (Exosome Diagnostics)
86
Exosome Diagnostics cci group
The impact of exosomes on pain behavior in <t>CCI</t> rats. (a) Mechanical paw withdrawal threshold (PWT) of rats in Sham group, CCI group, <t>and</t> <t>Exo</t> group. (b) Thermal withdrawal latency (PWL) of rats in Sham group, CCI group, and Exo group ns indicates p > 0.05; * denotes the difference between the Exo group and the CCI group; # denotes the difference between the Sham group and the CCI group; **** p < 0.001; #### p < 0.001.
Cci Group, supplied by Exosome Diagnostics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cci group/product/Exosome Diagnostics
Average 86 stars, based on 1 article reviews
cci group - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier
cci 779  (MedChemExpress)
94
MedChemExpress cci 779
The impact of exosomes on pain behavior in <t>CCI</t> rats. (a) Mechanical paw withdrawal threshold (PWT) of rats in Sham group, CCI group, <t>and</t> <t>Exo</t> group. (b) Thermal withdrawal latency (PWL) of rats in Sham group, CCI group, and Exo group ns indicates p > 0.05; * denotes the difference between the Exo group and the CCI group; # denotes the difference between the Sham group and the CCI group; **** p < 0.001; #### p < 0.001.
Cci 779, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cci 779/product/MedChemExpress
Average 94 stars, based on 1 article reviews
cci 779 - by Bioz Stars, 2026-05
94/100 stars
  Buy from Supplier
cci  (Wolters Kluwer Health)
86
Wolters Kluwer Health cci
The impact of exosomes on pain behavior in <t>CCI</t> rats. (a) Mechanical paw withdrawal threshold (PWT) of rats in Sham group, CCI group, <t>and</t> <t>Exo</t> group. (b) Thermal withdrawal latency (PWL) of rats in Sham group, CCI group, and Exo group ns indicates p > 0.05; * denotes the difference between the Exo group and the CCI group; # denotes the difference between the Sham group and the CCI group; **** p < 0.001; #### p < 0.001.
Cci, supplied by Wolters Kluwer Health, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cci/product/Wolters Kluwer Health
Average 86 stars, based on 1 article reviews
cci - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier
impact cci device  (Zhongshi Duqing Biotech Co Ltd)
86
Zhongshi Duqing Biotech Co Ltd impact cci device
The impact of exosomes on pain behavior in <t>CCI</t> rats. (a) Mechanical paw withdrawal threshold (PWT) of rats in Sham group, CCI group, <t>and</t> <t>Exo</t> group. (b) Thermal withdrawal latency (PWL) of rats in Sham group, CCI group, and Exo group ns indicates p > 0.05; * denotes the difference between the Exo group and the CCI group; # denotes the difference between the Sham group and the CCI group; **** p < 0.001; #### p < 0.001.
Impact Cci Device, supplied by Zhongshi Duqing Biotech Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/impact cci device/product/Zhongshi Duqing Biotech Co Ltd
Average 86 stars, based on 1 article reviews
impact cci device - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier

Image Search Results


The PI3K/Akt/mTOR pathway is essential for HAdV-11 replication in ESCC cell lines. ( A ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, the mRNA expression levels were determined using quantitative polymerase chain reaction (qPCR). ( B , D , E , F , H and I ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, and Western blot analysis of mTOR, p-DRP1, PARK2, LC3 and GPX4 expression. ( C ) Cells were pretreated with Temsirolimus (CCI-779) (10 nM) for 2 h, and then infected with HAdV-11 at an MOI of 2 for 48 h. The mitochondrial mass was estimated by MTG staining. ( H ) After pretreatment with 0.5 µM mTOR agonist (MHY1485) for 2 h, cells were infected with HAdV-11 at a MOI of 2 for 48 h. Subsequently, the cells were stained with either C11-BODIPY or Fe 2+ and quantified using flow cytometry. ( J ) Cells were pretreated with CCI-779 for 2 h, and then infected with HAdV-11 at an MOI of 2 for 72 h. Infectious virus production was assessed by titration on JH293 cells and the titer as PFU/cell calculated. The half maximal effective concentration (EC50) for each sample was calculated. Data are cumulative results from 3 experiments ( A , J ) or are representative of 3 independent experiments ( B , C , D , E , F , G , H , I ). Data are presented as mean ± SD ( A , C , E , F , G , H , I , J ). Differences analyzed using a one-way ANOVA with Bonferroni’s post hoc correction ( C , E , F , G , H , I ) or two-tailed t-test ( A , J ) ( n = 3)

Journal: BMC Cancer

Article Title: Oncolytic adenovirus type 11-induced ferroptosis of esophageal squamous cell carcinoma cells involves in mitochondrial impairment and the mTOR pathway

doi: 10.1186/s12885-026-15735-7

Figure Lengend Snippet: The PI3K/Akt/mTOR pathway is essential for HAdV-11 replication in ESCC cell lines. ( A ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, the mRNA expression levels were determined using quantitative polymerase chain reaction (qPCR). ( B , D , E , F , H and I ) Cells were treated with HAdV-11 for 72 h at an MOI of 2 PFU/cell, and Western blot analysis of mTOR, p-DRP1, PARK2, LC3 and GPX4 expression. ( C ) Cells were pretreated with Temsirolimus (CCI-779) (10 nM) for 2 h, and then infected with HAdV-11 at an MOI of 2 for 48 h. The mitochondrial mass was estimated by MTG staining. ( H ) After pretreatment with 0.5 µM mTOR agonist (MHY1485) for 2 h, cells were infected with HAdV-11 at a MOI of 2 for 48 h. Subsequently, the cells were stained with either C11-BODIPY or Fe 2+ and quantified using flow cytometry. ( J ) Cells were pretreated with CCI-779 for 2 h, and then infected with HAdV-11 at an MOI of 2 for 72 h. Infectious virus production was assessed by titration on JH293 cells and the titer as PFU/cell calculated. The half maximal effective concentration (EC50) for each sample was calculated. Data are cumulative results from 3 experiments ( A , J ) or are representative of 3 independent experiments ( B , C , D , E , F , G , H , I ). Data are presented as mean ± SD ( A , C , E , F , G , H , I , J ). Differences analyzed using a one-way ANOVA with Bonferroni’s post hoc correction ( C , E , F , G , H , I ) or two-tailed t-test ( A , J ) ( n = 3)

Article Snippet: Mitochondrial division inhibitor 1 (Mdivi-1), Ferrostatin-1, Erastin, MK2206, LY294002 and Temsirolimus (CCI-779) were purchased from MedChem Express (Shanghai, China).

Techniques: Expressing, Real-time Polymerase Chain Reaction, Western Blot, Infection, Staining, Flow Cytometry, Virus, Titration, Concentration Assay, Two Tailed Test

The impact of exosomes on pain behavior in CCI rats. (a) Mechanical paw withdrawal threshold (PWT) of rats in Sham group, CCI group, and Exo group. (b) Thermal withdrawal latency (PWL) of rats in Sham group, CCI group, and Exo group ns indicates p > 0.05; * denotes the difference between the Exo group and the CCI group; # denotes the difference between the Sham group and the CCI group; **** p < 0.001; #### p < 0.001.

Journal: Molecular Pain

Article Title: Mechanism of human umbilical cord mesenchymal stem cell-derived exosomes in alleviating neuropathic pain in CCI rats

doi: 10.1177/17448069261417109

Figure Lengend Snippet: The impact of exosomes on pain behavior in CCI rats. (a) Mechanical paw withdrawal threshold (PWT) of rats in Sham group, CCI group, and Exo group. (b) Thermal withdrawal latency (PWL) of rats in Sham group, CCI group, and Exo group ns indicates p > 0.05; * denotes the difference between the Exo group and the CCI group; # denotes the difference between the Sham group and the CCI group; **** p < 0.001; #### p < 0.001.

Article Snippet: Relative to the CCI group, exosome-treated rats (Exo group) showed no statistically significant difference in PWT ( p > 0.05), but exhibited a marked increase in PWL ( p < 0.001).

Techniques:

The effect of exosomes on inflammatory factors in the spinal dorsal horn of CCI rats. (a–c) represent the intra-group and inter-group comparison results of NF-κB, TNF-α, and IL-6 at D7 and D14 in the spinal cord Sham group, CCI group, and Exo group, respectively. Here, ns p > 0.05; * p < 0.05; ** p < 0.01; **** p < 0.001.

Journal: Molecular Pain

Article Title: Mechanism of human umbilical cord mesenchymal stem cell-derived exosomes in alleviating neuropathic pain in CCI rats

doi: 10.1177/17448069261417109

Figure Lengend Snippet: The effect of exosomes on inflammatory factors in the spinal dorsal horn of CCI rats. (a–c) represent the intra-group and inter-group comparison results of NF-κB, TNF-α, and IL-6 at D7 and D14 in the spinal cord Sham group, CCI group, and Exo group, respectively. Here, ns p > 0.05; * p < 0.05; ** p < 0.01; **** p < 0.001.

Article Snippet: Relative to the CCI group, exosome-treated rats (Exo group) showed no statistically significant difference in PWT ( p > 0.05), but exhibited a marked increase in PWL ( p < 0.001).

Techniques: Comparison

Changes in mRNA content of A1, A2, and GFAP in spinal cord astrocytes of CCI rats treated with exosomes. (a–c) Represent the intra-group and inter-group comparison results of GFAP, S100A10 mRNA, and C3 mRNA in the spinal dorsal horn at D7 and D14 for the Sham group, CCI group, and Exo group, respectively. ns p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Journal: Molecular Pain

Article Title: Mechanism of human umbilical cord mesenchymal stem cell-derived exosomes in alleviating neuropathic pain in CCI rats

doi: 10.1177/17448069261417109

Figure Lengend Snippet: Changes in mRNA content of A1, A2, and GFAP in spinal cord astrocytes of CCI rats treated with exosomes. (a–c) Represent the intra-group and inter-group comparison results of GFAP, S100A10 mRNA, and C3 mRNA in the spinal dorsal horn at D7 and D14 for the Sham group, CCI group, and Exo group, respectively. ns p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Article Snippet: Relative to the CCI group, exosome-treated rats (Exo group) showed no statistically significant difference in PWT ( p > 0.05), but exhibited a marked increase in PWL ( p < 0.001).

Techniques: Comparison

Changes in A1 and A2 protein content in spinal cord astrocytes of CCI rats treated with exosomes. (a–d) Represent the intra-group and inter-group comparison results of C3 and S100A10 in the spinal dorsal horn at D7 and D14 for the Sham group, CCI group, and Exo group, respectively. Here, ns p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Journal: Molecular Pain

Article Title: Mechanism of human umbilical cord mesenchymal stem cell-derived exosomes in alleviating neuropathic pain in CCI rats

doi: 10.1177/17448069261417109

Figure Lengend Snippet: Changes in A1 and A2 protein content in spinal cord astrocytes of CCI rats treated with exosomes. (a–d) Represent the intra-group and inter-group comparison results of C3 and S100A10 in the spinal dorsal horn at D7 and D14 for the Sham group, CCI group, and Exo group, respectively. Here, ns p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Article Snippet: Relative to the CCI group, exosome-treated rats (Exo group) showed no statistically significant difference in PWT ( p > 0.05), but exhibited a marked increase in PWL ( p < 0.001).

Techniques: Comparison