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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
Cartridges, supplied by Seiko Epson Corporation, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Analyte recovery under a variety of conditions. (A) Automated <t>pTau217</t> assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.
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Analyte recovery under a variety of conditions. (A) Automated pTau217 assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.

Journal: medRxiv

Article Title: Multi-Platform Comparison of Plasma Phosphorylated Tau Assays: Analytical and Workflow Factors Drive Clinical Implementation Decisions

doi: 10.64898/2026.05.04.26352262

Figure Lengend Snippet: Analyte recovery under a variety of conditions. (A) Automated pTau217 assays remained within ±5% of baseline after up to 6 freeze/thaw cycles, with pTau181 remaining within ±20%, and the one manual assay (MSD pTau217) exceeding 20% after only 2 cycles. (B-D) All assays tested were robust to interference by hemolysate and lipemia, with a trend towards negative interference with icteric specimens.

Article Snippet: Reagents from Fujirebio included Lumipulse G pTau217 Plasma Immunoreaction Cartridges (#81472) with associated controls and calibrators.

Techniques: