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(A) Mutation profiles from targeted capture <t>sequencing</t> of injected muscle tissues (S18–S19) and tumors (S1–S17), including three tumors with additional Pten mutations (S9, S13, S14). (B) Top 10 most frequently mutated genes across all tumors.
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(A) Mutation profiles from targeted capture sequencing of injected muscle tissues (S18–S19) and tumors (S1–S17), including three tumors with additional Pten mutations (S9, S13, S14). (B) Top 10 most frequently mutated genes across all tumors.

Journal: bioRxiv

Article Title: A tailored in vivo CRISPR screen identifies BAP1 as a potent tumor suppressor of soft tissue sarcoma

doi: 10.64898/2025.12.01.691734

Figure Lengend Snippet: (A) Mutation profiles from targeted capture sequencing of injected muscle tissues (S18–S19) and tumors (S1–S17), including three tumors with additional Pten mutations (S9, S13, S14). (B) Top 10 most frequently mutated genes across all tumors.

Article Snippet: The capture sequencing was done in Azenta.

Techniques: Mutagenesis, Sequencing, Injection