Journal: Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring

Article Title: Current advances in digital cognitive assessment for preclinical Alzheimer's disease

doi: 10.1002/dad2.12217

Figure Lengend Snippet: Validation of primarily in‐clinic computerized and tablet‐based cognitive assessment

Article Snippet: A more recent iteration of Cogstate tasks is the C3 (Computerized Cognitive Composite) which includes the CBB in addition to two measures potentially sensitive to changes in early AD based on evidence from the cognitive neuroscience literature: the Behavioral Pattern Separation–Object Version (BPS‐O) and The Face‐Name Associative Memory Test (FNAME).

Techniques: Biomarker Discovery

Journal: The journal of prevention of Alzheimer's disease

Article Title: Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries

doi: 10.14283/jpad.2017.1

Figure Lengend Snippet: Participant characteristics and cognitive performance

Article Snippet: Two computerized batteries that are of particular relevance to these questions are the Cogstate Computerized Cognitive Composite (C3) battery ( 1 ), which is currently being used in the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) secondary prevention trial ( 9 ), and the newly developed, non-proprietary iPad version of the National Institutes of Health (NIH) Toolbox Cognition Battery (NIHTB-CB) (for reference to the general computerized battery: 14, 15).

Techniques:

Journal: The journal of prevention of Alzheimer's disease

Article Title: Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries

doi: 10.14283/jpad.2017.1

Figure Lengend Snippet: Regression and ROC analyses with each computerized composite to predict subtle cognitive impairment or typical performance on the PACC

Article Snippet: Two computerized batteries that are of particular relevance to these questions are the Cogstate Computerized Cognitive Composite (C3) battery ( 1 ), which is currently being used in the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) secondary prevention trial ( 9 ), and the newly developed, non-proprietary iPad version of the National Institutes of Health (NIH) Toolbox Cognition Battery (NIHTB-CB) (for reference to the general computerized battery: 14, 15).

Techniques:

Journal: The journal of prevention of Alzheimer's disease

Article Title: Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries

doi: 10.14283/jpad.2017.1

Figure Lengend Snippet: Scatterplot of association between NIHTB-CB and Cogstate C3 battery, with slopes estimating group effect of high and low PACC performance

Article Snippet: Two computerized batteries that are of particular relevance to these questions are the Cogstate Computerized Cognitive Composite (C3) battery ( 1 ), which is currently being used in the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) secondary prevention trial ( 9 ), and the newly developed, non-proprietary iPad version of the National Institutes of Health (NIH) Toolbox Cognition Battery (NIHTB-CB) (for reference to the general computerized battery: 14, 15).

Techniques: Battery

Journal: The journal of prevention of Alzheimer's disease

Article Title: Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries

doi: 10.14283/jpad.2017.1

Figure Lengend Snippet: ROCs for the NIHTB-CB and Cogstate C3 composites, and the C3 FNLT task alone to distinguish between high and low PACC performance (Blue = C3 Learning-Memory, Red = NIHTB-CB, Green = C3 Processing Speed-Attention, Grey = C3 FNLT, Black-dash = NIH PSMT)

Article Snippet: Two computerized batteries that are of particular relevance to these questions are the Cogstate Computerized Cognitive Composite (C3) battery ( 1 ), which is currently being used in the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) secondary prevention trial ( 9 ), and the newly developed, non-proprietary iPad version of the National Institutes of Health (NIH) Toolbox Cognition Battery (NIHTB-CB) (for reference to the general computerized battery: 14, 15).

Techniques:

Journal: The journal of prevention of Alzheimer's disease

Article Title: Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries

doi: 10.14283/jpad.2017.1

Figure Lengend Snippet: Diagrammatic representation of each composite arising from the Cogstate C3 and NIHTH-CB computerized batteries, and their corresponding tests. Each composite is also attached to an odds ratio (OR) which represents the ability of each composite to distinguish between typical and subtly impaired PACC performance. The pink boxes denote the tasks that were most contributory to the variance explained in the logistic regression model

Article Snippet: Two computerized batteries that are of particular relevance to these questions are the Cogstate Computerized Cognitive Composite (C3) battery ( 1 ), which is currently being used in the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) secondary prevention trial ( 9 ), and the newly developed, non-proprietary iPad version of the National Institutes of Health (NIH) Toolbox Cognition Battery (NIHTB-CB) (for reference to the general computerized battery: 14, 15).

Techniques: