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Genome analysis that identified recombination in sequence type (ST) 468 strains of group B Streptococcus . Plotting of polymorphisms identified in ST468 strains (PF-10, PF-17, and PF-18 in red, blue, and green, respectively) relative to the genome of the ST452 strain NGBS572 shows areas of densely clustered polymorphisms between positions 210,000 and 320,000 bp. Genome landmarks, such as mobile genetic elements (gray), multilocus sequence typing genes (light blue), pilus (brown), and virulence genes (dark pink), are marked in the outer circle. Precise areas of recombination in ST468 strains defined by <t>BRAT</t> <t>NextGen</t> are depicted in gold (PF-10), purple (PF-17), and orange (PF-18). Mbp, megabase pairs.
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https://www.bioz.com/product/brat+nextgen/pmc05088005-14-10-11?v=NextGen+Sciences
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Genome analysis that identified recombination in sequence type (ST) 468 strains of group B Streptococcus . Plotting of polymorphisms identified in ST468 strains (PF-10, PF-17, and PF-18 in red, blue, and green, respectively) relative to the genome of the ST452 strain NGBS572 shows areas of densely clustered polymorphisms between positions 210,000 and 320,000 bp. Genome landmarks, such as mobile genetic elements (gray), multilocus sequence typing genes (light blue), pilus (brown), and virulence genes (dark pink), are marked in the outer circle. Precise areas of recombination in ST468 strains defined by BRAT NextGen are depicted in gold (PF-10), purple (PF-17), and orange (PF-18). Mbp, megabase pairs.

Journal: Emerging Infectious Diseases

Article Title: Serotype IV Sequence Type 468 Group B Streptococcus Neonatal Invasive Disease, Minnesota, USA

doi: 10.3201/eid2211.152031

Figure Lengend Snippet: Genome analysis that identified recombination in sequence type (ST) 468 strains of group B Streptococcus . Plotting of polymorphisms identified in ST468 strains (PF-10, PF-17, and PF-18 in red, blue, and green, respectively) relative to the genome of the ST452 strain NGBS572 shows areas of densely clustered polymorphisms between positions 210,000 and 320,000 bp. Genome landmarks, such as mobile genetic elements (gray), multilocus sequence typing genes (light blue), pilus (brown), and virulence genes (dark pink), are marked in the outer circle. Precise areas of recombination in ST468 strains defined by BRAT NextGen are depicted in gold (PF-10), purple (PF-17), and orange (PF-18). Mbp, megabase pairs.

Article Snippet: To confirm this hypothesis, we analyzed the polymorphism data with BRAT NextGen , run with 20 iterations, 100 replicates, and a significance cutoff of 0.05.

Techniques: Sequencing