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( a ) Sanger sequencing; ( b ) pyrosequencing-based assay U-BRAF V600 . “+” indicates the positive peaks of the dispensation nucleotides within recognition patterns of U-BRAF V600 assay. mt – mutant; wt – wild-type. Recognition patterns are shown in black boxes.

Journal: PLoS ONE

Article Title: Automated Universal BRAF State Detection within the Activation Segment in Skin Metastases by Pyrosequencing-Based Assay U-BRAF V600

doi: 10.1371/journal.pone.0059221

Figure Lengend Snippet: ( a ) Sanger sequencing; ( b ) pyrosequencing-based assay U-BRAF V600 . “+” indicates the positive peaks of the dispensation nucleotides within recognition patterns of U-BRAF V600 assay. mt – mutant; wt – wild-type. Recognition patterns are shown in black boxes.

Article Snippet: Furthermore, in we present the algorithm for automation of BRAF state classification of U-BRAF V600 pyrosequencing data analysis taking into consideration the individual features of each mutation variant shown in .

Techniques: Sequencing, Pyrosequencing Assay, Mutagenesis

Recognition patterns for 36 BRAF mutations by U-BRAF V600 assay.

Journal: PLoS ONE

Article Title: Automated Universal BRAF State Detection within the Activation Segment in Skin Metastases by Pyrosequencing-Based Assay U-BRAF V600

doi: 10.1371/journal.pone.0059221

Figure Lengend Snippet: Recognition patterns for 36 BRAF mutations by U-BRAF V600 assay.

Article Snippet: Furthermore, in we present the algorithm for automation of BRAF state classification of U-BRAF V600 pyrosequencing data analysis taking into consideration the individual features of each mutation variant shown in .

Techniques: Mutagenesis