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A summary of selected articles in this systematic review

Journal: Translational Psychiatry

Article Title: What do DNA methylation studies tell us about depression? A systematic review

doi: 10.1038/s41398-019-0412-y

Figure Lengend Snippet: A summary of selected articles in this systematic review

Article Snippet: 65 , Olsson et al. , 2010 , Australia , 150 , Australian adolescents (cases and controls) , Case–control , MDD , Buccal cells , Bisulfite conversion, Sequenom MassARRAY EpiTyping , SLC6A4 , Promoters, CpG islands , There was no association between depressive symptoms and either buccal cell 5-HTT methylation or 5-HTTLPR. Depressive symptoms were more common among those with elevated buccal cell 5-HTT methylation who carried a 5-HTTLPR short allele.

Techniques: DNA Methylation Assay, Genome Wide, Methylation, Variant Assay, Derivative Assay, Biomarker Assay, Expressing, Software, Binding Assay, Sequencing, EpiTYPER Assay, CpG Methylation Assay, Enzyme-linked Immunosorbent Assay, Immunoprecipitation, Methylated DNA Immunoprecipitation Sequencing, Real-time Polymerase Chain Reaction, SYBR Green Assay, Marker

Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.

Journal: Journal of Experimental Neuroscience

Article Title: Epigenetic Mechanisms of the Aging Human Retina

doi: 10.4137/JEN.S25513

Figure Lengend Snippet: Genome-wide epigenetic studies of retinal disease, risk factors, and related pathologies.

Article Snippet: Ko et al, 2013 , Renal , Kidney fibrosis , Discovery: HELP-Nimblegen whole genome covering microarray; validation: bisulfite-Sequenom MassArray EpiTYPER; replication: Illumina Infinium HumanMethylation450K BeadChip , None , Discovery/validation: 12 hypertensive or diabetic chronic kidney disease, 14 controls; replication: 21 diabetic chronic kidney disease, 66 controls , Human kidney tubule epithelial cell tissue samples from healthy living transplants or surgical nephrectomies , Not provided , Discovery: 4751 DMRs/1535 genes; replication: 1061 genes , Cell adhesion, development , COLIVA1, DSCAM, DPT.

Techniques: Genome Wide, RNA Expression, Preserving, Methylation, Microarray, Immunohistochemistry, Western Blot, Activity Assay, Binding Assay, Methylated DNA Immunoprecipitation, Biomarker Discovery, DNA Methylation Assay, Cell Culture, Extraction, Methylation Sequencing, Transformation Assay, Sequencing, Methylated DNA Immunoprecipitation Sequencing, Phospho-proteomics, Glycoproteomics, Luciferase, Starch, In Vitro, Expressing, Transduction, Ubiquitin Proteomics, Clinical Proteomics, Membrane, Cell Differentiation, Control